The chalcone synthase superfamily of type III polyketide synthases.

The tropical plant family Piperaceae has provided many past and present civilizations with a source of diverse medicines and food grade spice. The secondary plant compounds that produce these desired qualities function also as chemical defenses for many species in the genus Piper. The compounds with the greatest insecticidal activity are the piperamides. Many studies have shown the effectiveness of Piper spp. extracts for the control of stored products pests and recently studies from our laboratory group have tested the extracts of Piper. nigrum, P. guineense and P. tuberculatum against insect pests of the home and garden. These results and those from investigations that examined the biochemical and molecular modes of action of the piperamides singly or in combination will be the focus of this review. The conclusions of our current work with Piperaceae are that Piper extracts offer a unique and useful source of biopesticide material for controlling small-scale insect out-breaks and reducing the likelihood of resistance development when applied as a synergist with other botanical insecticides such as pyrethrum.

A review of Piper spp. (Piperaceae) phytochemistry, insecticidal activity and mode of action

Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities

Chemical composition and larvicidal activity of essential oils from Piper species

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Sanjay K.Singh¶andJesper Wengel

Papers

Polyphenols and alkaloids from piper species