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Sanjeev Galande

Researcher at Indian Institute of Science

Publications -  100
Citations -  3752

Sanjeev Galande is an academic researcher from Indian Institute of Science. The author has contributed to research in topics: Chromatin & Gene. The author has an hindex of 28, co-authored 91 publications receiving 3362 citations. Previous affiliations of Sanjeev Galande include Shiv Nadar University & Savitribai Phule Pune University.

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Ku acts in a unique way at the mammalian telomere to prevent end joining

TL;DR: It is proposed that Ku localizes to internal regions of the telomere via a high-affinity interaction with TRF1, and acts in a unique way at theTelomere to prevent end joining.
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Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus

TL;DR: It is shown that PML physically and functionally interacts with the matrix attachment region (MAR)-binding protein, special AT-rich sequence binding protein 1 (SATB1) to organize the major histocompatibility complex (MHC) class I locus into distinct higher-order chromatin-loop structures.
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Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition

TL;DR: The results indicate that early stress may transiently endow animals with a potential adaptive advantage in stressful environments but across a life span is associated with long-term deleterious effects.
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Global Regulator SATB1 Recruits β-Catenin and Regulates TH2 Differentiation in Wnt-Dependent Manner

TL;DR: Chromatin organizer SATB1 and Wnt transducer β-catenin form a complex and regulate expression of GATA3 and TH2 cytokines in Wnt-dependent manner and orchestrate TH2 lineage commitment.
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p300-mediated Acetylation of Histone H3 Lysine 56 Functions in DNA Damage Response in Mammals

TL;DR: Interestingly, analysis of occurrence of H3K56 acetylation using ChIP-on-chip revealed its genome-wide spread, affecting genes involved in several pathways that are implicated in tumorigenesis such as cell cycle, DNA damage response, DNA repair, and apoptosis.