S
Sara Regnér
Researcher at Lund University
Publications - 73
Citations - 2659
Sara Regnér is an academic researcher from Lund University. The author has contributed to research in topics: Acute pancreatitis & Pancreatitis. The author has an hindex of 25, co-authored 62 publications receiving 2220 citations. Previous affiliations of Sara Regnér include Uppsala University Hospital & International Agency for Research on Cancer.
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Journal ArticleDOI
IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
Hong Zhang,Patrick Neuhöfer,Liang Song,Björn Rabe,Marina Lesina,Magdalena U. Kurkowski,Matthias Treiber,Thomas Wartmann,Sara Regnér,Henrik Thorlacius,Dieter Saur,Gregor Weirich,Akihiko Yoshimura,Walter Halangk,Joseph P. Mizgerd,Roland M. Schmid,Stefan Rose-John,Hana Algül +17 more
TL;DR: IL-6 trans-signaling is an essential mediator of ALI in SAP across species and it is suggested that therapeutic inhibition of IL-6 may prevent SAP-associated ALI.
Journal ArticleDOI
Hepatocellular Carcinoma Risk Factors and Disease Burden in a European Cohort: A Nested Case–Control Study
Dimitrios Trichopoulos,Dimitrios Trichopoulos,Christina Bamia,Pagona Lagiou,Pagona Lagiou,Pagona Lagiou,Veronika Fedirko,Elisabeth Trepo,Mazda Jenab,Tobias Pischon,Ute Nöthlings,Kim Overved,Anne Tjønneland,Malene Outzen,Françoise Clavel-Chapelon,Françoise Clavel-Chapelon,Rudolf Kaaks,Annekatrin Lukanova,Heiner Boeing,Krasimira Aleksandrova,Vassiliki Benetou,Dimosthenis Zylis,Domenico Palli,Valeria Pala,Salvatore Panico,Rosario Tumino,Carlotta Sacerdote,H. Bas Bueno-de-Mesquita,Henk J. van Kranen,Petra H.M. Peeters,Eiliv Lund,J. Ramón Quirós,Carlos González,María José Sánchez Pérez,Carmen Navarro,Miren Dorronsoro,Aurelio Barricarte,Björn Lindkvist,Sara Regnér,Mårten Werner,Göran Hallmans,Kay-Tee Khaw,Nicholas J. Wareham,Timothy J. Key,Isabelle Romieu,Shu Chun Chuang,Neil Murphy,Paolo Boffetta,Antonia Trichopoulou,Antonia Trichopoulou,Elio Riboli +50 more
TL;DR: Smoking contributed to more hepatocellular carcinomas in this Europe-wide cohort than chronic HBV and HCV infections and heavy alcohol consumption and obesity also contributed to sizeable fractions of this disease burden.
Journal ArticleDOI
Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Genevieve Buckland,Antonio Agudo,Leila Luján,Paula Jakszyn,H. Bas Bueno-de-Mesquita,Domenico Palli,Heiner Boeing,Fátima Carneiro,Vittorio Krogh,Carlotta Sacerdote,Rosario Tumino,Salvatore Panico,Gabriella Nesi,Jonas Manjer,Sara Regnér,Ingegerd Johansson,Roger Stenling,María José Sánchez,Miren Dorronsoro,Aurelio Barricarte,Carmen Navarro,J. Ramón Quirós,Naomi E. Allen,Timothy J. Key,Sheila Bingham,Rudolf Kaaks,Kim Overvad,Majken K. Jensen,Anja Olsen,Anne Tjønneland,Petra H.M. Peeters,Mattijs E. Numans,Marga C. Ocké,Françoise Clavel-Chapelon,Sophie Morois,Marie-Christine Boutron-Ruault,Antonia Trichopoulou,Pagona Lagiou,Dimitrios Trichopoulos,Eiliv Lund,Elisabeth Couto,Paolo Boffeta,Mazda Jenab,Elio Riboli,Dora Romaguera,Traci Mouw,Carlos A. González +46 more
TL;DR: Greater adherence to an rMED is associated with a significant reduction in the risk of incident GC, and there was no evidence of heterogeneity between different anatomic locations or histologic types.
Journal ArticleDOI
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis
Mohammed Merza,Hannes Hartman,Milladur Rahman,Rundk Hwaiz,Enming Zhang,Erik Renström,Lingtao Luo,Matthias Mörgelin,Sara Regnér,Henrik Thorlacius +9 more
TL;DR: NETs regulate organ inflammation and injury in mice with AP, and might be targeted to reduce pancreatic tissue damage and inflammation in patients.
Journal ArticleDOI
Abdominal obesity, weight gain during adulthood and risk of liver and biliary tract cancer in a European cohort
Sabrina Schlesinger,Krasimira Aleksandrova,Tobias Pischon,Veronika Fedirko,Mazda Jenab,Elisabeth Trepo,Paolo Boffetta,Christina C. Dahm,Christina C. Dahm,Kim Overvad,Anne Tjønneland,Jytte Halkjær,Guy Fagherazzi,Guy Fagherazzi,Marie-Christine Boutron-Ruault,Marie-Christine Boutron-Ruault,Franck Carbonnel,Franck Carbonnel,Rudolf Kaaks,Annekatrin Lukanova,Heiner Boeing,Antonia Trichopoulou,Christina Bamia,Pagona Lagiou,Pagona Lagiou,Pagona Lagiou,Domenico Palli,Sara Grioni,Salvatore Panico,Rosario Tumino,Paolo Vineis,H. B. Bueno-de-Mesquita,Saskia W. van den Berg,Petra H.M. Peeters,Petra H.M. Peeters,Tonje Braaten,Elisabete Weiderpass,J. Ramón Quirós,Noémie Travier,María José Sánchez,Carmen Navarro,Aurelio Barricarte,Miren Dorronsoro,Björn Lindkvist,Sara Regnér,Mårten Werner,Malin Sund,Kay-Tee Khaw,Nicholas J. Wareham,Ruth C. Travis,Teresa Norat,Petra A. Wark,Elio Riboli,Ute Nöthlings +53 more
TL;DR: Evidence of an association between obesity, particularly abdominal obesity, and risk of HCC and GBC is provided and public health recommendations to reduce the prevalence of obesity and weight gain in adulthood for HCCand GBC prevention in Western populations are supported.