Sarah Anderl-Straub

TL;DR: Neurofilaments in CSF have a high relevance for the differential diagnosis of MNDs and should be included in the diagnostic work-up of patients and their value as prognostic markers should be investigated further.

TL;DR: An international study of age at symptom onset, age at death, and disease duration in individuals with mutations in GRN, MAPT, and C9orf72 to investigate the extent to which variability in age at onset and at death could be accounted for by family membership and the specific mutation carried.

TL;DR: Serum GFAP correlated with the Mini-Mental State Examination score and might be a follow-up marker in clinical trials and the first blood biomarker in the differential diagnosis of AD and bvFTD.

TL;DR: In this article, the authors assess the agreement between data on cerebral amyloidosis derived using Pittsburgh compound B positron emission tomography and (i) multi-laboratory INNOTEST enzyme linked immunosorbent assay derived cerebrospinal fluid concentrations of amyloids-β42; and (ii) centrally measured cerebrainsinal fluid amylhead-β 42 using a Meso Scale Discovery enzyme-linked immunosorbent assay.

TL;DR: The data indicate that neuroinflammation is linked to the symptomatic phase of ALS/FTD and shows a similar pattern in sporadic and genetic cases.