S
Sarah M. Fortune
Researcher at Harvard University
Publications - 191
Citations - 16777
Sarah M. Fortune is an academic researcher from Harvard University. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 57, co-authored 157 publications receiving 12685 citations. Previous affiliations of Sarah M. Fortune include University of Auckland & Wellcome Trust.
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Journal ArticleDOI
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
Carly G. K. Ziegler,Samuel J. Allon,Sarah K. Nyquist,Ian M. Mbano,Vincent N. Miao,Constantine N. Tzouanas,Yuming Cao,Ashraf S. Yousif,Julia Bals,Blake M. Hauser,Blake M. Hauser,Jared Feldman,Jared Feldman,Christoph Muus,Christoph Muus,Marc H. Wadsworth,Samuel W. Kazer,Travis K. Hughes,Benjamin Doran,G. James Gatter,G. James Gatter,G. James Gatter,Marko Vukovic,Faith Taliaferro,Faith Taliaferro,Benjamin E. Mead,Zhiru Guo,Jennifer P. Wang,Delphine Gras,Magali Plaisant,Meshal Ansari,Ilias Angelidis,Heiko Adler,Jennifer M.S. Sucre,Chase J. Taylor,Brian M. Lin,Avinash Waghray,Vanessa Mitsialis,Vanessa Mitsialis,Daniel F. Dwyer,Kathleen M. Buchheit,Joshua A. Boyce,Nora A. Barrett,Tanya M. Laidlaw,Shaina L. Carroll,Lucrezia Colonna,Victor Tkachev,Victor Tkachev,Christopher W. Peterson,Christopher W. Peterson,Alison Yu,Alison Yu,Hengqi Betty Zheng,Hengqi Betty Zheng,Hannah P. Gideon,Caylin G. Winchell,Philana Ling Lin,Philana Ling Lin,Colin D. Bingle,Scott B. Snapper,Scott B. Snapper,Jonathan A. Kropski,Jonathan A. Kropski,Fabian J. Theis,Herbert B. Schiller,Laure-Emmanuelle Zaragosi,Pascal Barbry,Alasdair Leslie,Alasdair Leslie,Hans-Peter Kiem,Hans-Peter Kiem,JoAnne L. Flynn,Sarah M. Fortune,Sarah M. Fortune,Sarah M. Fortune,Bonnie Berger,Robert W. Finberg,Leslie S. Kean,Leslie S. Kean,Manuel Garber,Aaron G. Schmidt,Aaron G. Schmidt,Daniel Lingwood,Alex K. Shalek,Jose Ordovas-Montanes,Nicholas E. Banovich,Alvis Brazma,Tushar J. Desai,Thu Elizabeth Duong,Oliver Eickelberg,Christine S. Falk,Michael Farzan,Ian A. Glass,Muzlifah Haniffa,Peter Horvath,Deborah T. Hung,Naftali Kaminski,Mark A. Krasnow,Malte Kühnemund,Robert Lafyatis,Haeock Lee,Sylvie Leroy,Sten Linnarson,Joakim Lundeberg,Kerstin B. Meyer,Alexander V. Misharin,Martijn C. Nawijn,Marko Nikolic,Dana Pe'er,Joseph E. Powell,Stephen R. Quake,Jay Rajagopal,Purushothama Rao Tata,Emma L. Rawlins,Aviv Regev,Paul A. Reyfman,Mauricio Rojas,Orit Rosen,Kourosh Saeb-Parsy,Christos Samakovlis,Herbert B. Schiller,Joachim L. Schultze,Max A. Seibold,Douglas P. Shepherd,Jason R. Spence,Avrum Spira,Xin Sun,Sarah A. Teichmann,Fabian J. Theis,Alexander M. Tsankov,Maarten van den Berge,Michael von Papen,Jeffrey A. Whitsett,Ramnik J. Xavier,Yan Xu,Kun Zhang +135 more
TL;DR: The data suggest that SARS-CoV-2 could exploit species-specific interferon-driven upregulation of ACE2, a tissue-protective mediator during lung injury, to enhance infection.
Journal ArticleDOI
Definitions and guidelines for research on antibiotic persistence
Naomi N.Q. Balaban,Sophie Helaine,Kim Lewis,Martin Ackermann,Martin Ackermann,Bree B. Aldridge,Dan I. Andersson,Mark P. Brynildsen,Dirk Bumann,Andrew Camilli,James J. Collins,James J. Collins,James J. Collins,Christoph Dehio,Sarah M. Fortune,Jean-Marc Ghigo,Wolf-Dietrich Hardt,Alexander Harms,Matthias Heinemann,Deborah T. Hung,Urs Jenal,Bruce R. Levin,Jan Michiels,Gisela Storz,Man-Wah Tan,Tanel Tenson,Laurence Van Melderen,Annelies S. Zinkernagel +27 more
TL;DR: Scientists working on the response of bacteria to antibiotics define antibiotic persistence and provide practical guidance on how to study bacterial persister cells, and provide a guide to measuring persistence.
Journal ArticleDOI
Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput
Todd M. Gierahn,Marc H. Wadsworth,Marc H. Wadsworth,Marc H. Wadsworth,Travis K. Hughes,Travis K. Hughes,Travis K. Hughes,Bryan D. Bryson,Bryan D. Bryson,Andrew Butler,Rahul Satija,Sarah M. Fortune,Sarah M. Fortune,J. Christopher Love,J. Christopher Love,J. Christopher Love,Alex K. Shalek,Alex K. Shalek,Alex K. Shalek +18 more
TL;DR: Seq-Well is presented, a portable, low-cost platform for massively parallel single-cell RNA-seq that is used to profile thousands of primary human macrophages exposed to Mycobacterium tuberculosis.
Journal ArticleDOI
Beyond binding: antibody effector functions in infectious diseases.
TL;DR: Antibodies play an essential role in host defence against pathogens by recognizing microorganisms or infected cells as mentioned in this paper, and they can control and eradicate infections through a variety of other mechanisms.
Journal ArticleDOI
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis.
Michael A. DeJesus,Elias R. Gerrick,Weizhen Xu,Sae Woong Park,Jarukit E. Long,Cara C. Boutte,Eric J. Rubin,Dirk Schnappinger,Sabine Ehrt,Sarah M. Fortune,Christopher M. Sassetti,Christopher M. Sassetti,Thomas R. Ioerger +12 more
TL;DR: This work provides an authoritative catalog of essential regions of the M. tuberculosis genome and a statistical framework for applying saturating mutagenesis to other bacteria.