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Sarah Tuttleton
Researcher at Aaron Diamond AIDS Research Center
Publications - 3
Citations - 1884
Sarah Tuttleton is an academic researcher from Aaron Diamond AIDS Research Center. The author has contributed to research in topics: Viral replication & Viral load. The author has an hindex of 3, co-authored 3 publications receiving 1853 citations.
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Journal ArticleDOI
Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus-infected macaques
Xia Jin,Daniel E. Bauer,Sarah Tuttleton,Sharon R Lewin,Agegnehu Gettie,James Blanchard,Craig E. Irwin,Jeffrey T. Safrit,John E. Mittler,Leor S. Weinberger,Leondios G. Kostrikis,Linqi Zhang,Alan S. Perelson,David D. Ho +13 more
TL;DR: It is demonstrated that CD8 cells play a crucial role in suppressing SIV replication in vivo and are examined using an anti-CD8 monoclonal antibody, OKT8F.
Journal ArticleDOI
Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy.
Linqi Zhang,Sharon R Lewin,Martin Markowitz,Hsi-Hsun Lin,Eva Skulsky,Rose Karanicolas,Yuxian He,Xia Jin,Sarah Tuttleton,Mika Vesanen,Hans M. L. Spiegel,Rhonda G. Kost,Jan van Lunzen,Hans-Juergen Stellbrink,Steven M. Wolinsky,William Borkowsky,Paul Palumbo,Leondios G. Kostrikis,David D. Ho +18 more
TL;DR: Overall, it is difficult to invoke thymic regenerative failure as a generalized mechanism for CD4 lymphocyte depletion in HIV-1 infection, as α1 circle numbers are normal in a substantial subset of HIV–1–infected individuals.
Journal ArticleDOI
Genetic characterization of vif, vpr, and vpu sequences from long-term survivors of human immunodeficiency virus type 1 infection
TL;DR: Phylogenetic analyses of the vif, vpr, and vpu sequences suggested that the HIV-1 strains found in the study subjects are not significantly different from those found in patients with AIDS and that the viruses in the LTS are unlikely to share a common genetic origin.