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Saripella Srikrishna

Researcher at Banaras Hindu University

Publications -  42
Citations -  1210

Saripella Srikrishna is an academic researcher from Banaras Hindu University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 18, co-authored 37 publications receiving 836 citations. Previous affiliations of Saripella Srikrishna include Institute of Medical Sciences, Banaras Hindu University.

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Journal ArticleDOI

DNA Binding and Anti-Cancer Activity of Redox-Active Heteroleptic Piano-Stool Ru(II), Rh(III), and Ir(III) Complexes Containing 4-(2-Methoxypyridyl)phenyldipyrromethene

Rakesh Kumar Gupta, +8 more
- 11 Mar 2013 - 
TL;DR: The results suggest that in vitro antitumor activity of 1-4 lies in the order 2 > 1 > 4 > 3.
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Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds.

Sandeep Singh, +4 more
- 01 Jan 2016 - 
TL;DR: This review carefully detail amyloid-β metabolism and its role in AD and the various genetic animal models used to evaluate therapeutics and the role of synthetic and plant-based compounds in therapeutics.
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Cancer Drug Development Using Drosophila as an in vivo Tool: From Bedside to Bench and Back

Amarish Kumar Yadav, +2 more
- 01 Sep 2016 - 
TL;DR: The fruit fly Drosophila melanogaster has been used for modeling cancer and as an in vivo tool for the validation and/or development of cancer therapeutics and is emerging as a powerful tool for high-throughput screening and should significantly reduce the cost and time associated with drug development.
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Synthesis and crystal structure determination of copper(II)-complex: In vitro DNA and HSA binding, pBR322 plasmid cleavage, cell imaging and cytotoxic studies.

Sartaj Tabassum, +6 more
- 18 Aug 2014 - 
TL;DR: To elucidate the mechanism of tumor inhibition, topoisomerase I enzymatic activity was carried out and further validated by cell imaging studies which clearly showed its nuclear localization.
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Chiral heterobimetallic complexes targeting human DNA-topoisomerase Iα

Sartaj Tabassum, +6 more
- 20 Nov 2013 - 
TL;DR: The gel electrophoretic patterns of supercoiled pBR322 DNA with varying concentrations of complex 3 exhibits the ability to cleave DNA and follow a freely diffusible radical mechanism and clearly demonstrates its potency to act as a chemotherapeutic agent.