S
Saumil J. Gandhi
Researcher at Albert Einstein College of Medicine
Publications - 5
Citations - 315
Saumil J. Gandhi is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 4, co-authored 5 publications receiving 286 citations. Previous affiliations of Saumil J. Gandhi include Yeshiva University.
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Transcription of functionally related constitutive genes is not coordinated
TL;DR: This work used highly sensitive fluorescence in situ hybridization (FISH) to count individual mRNAs of functionally related and unrelated genes within single Saccharomyces cerevisiae cells and revealed that transcript levels of temporally induced genes are highly correlated in individual cells.
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Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate
Sanford J. Silverman,Allegra A. Petti,Nikolai Slavov,Lance Parsons,Ryan Briehof,Stephan Y. Thiberge,Daniel Zenklusen,Saumil J. Gandhi,Daniel R. Larson,Robert H. Singer,David Botstein +10 more
TL;DR: The yeast metabolic cycle is an intrinsic property of yeast metabolism and does not depend on either synchronization or external limitation of growth by the carbon source.
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Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena INV-initiated invadopodium formation
Jeanine Pignatelli,Jose Javier Bravo-Cordero,Minna Roh-Johnson,Minna Roh-Johnson,Saumil J. Gandhi,Yarong Wang,Xiaoming Chen,Robert J. Eddy,Alice Xue,Robert H. Singer,Louis Hodgson,Maja H. Oktay,John S. Condeelis +12 more
TL;DR: A novel role for Notch1 signaling in the regulation of MenaINV expression and transendothelial migration is indicated and mechanistic information essential to the use of therapeutic inhibitors of metastasis is provided.
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Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
Rossanna C. Pezo,Saumil J. Gandhi,L. Andrew Shirley,Richard G. Pestell,Leonard H. Augenlicht,Robert H. Singer +5 more
TL;DR: A novel method of fluorescence in situ hybridization (FISH) that can detect transcriptional activation of individual genes at their site in single cells in the interphase nucleus is developed and is predictive of response to 5-FU in a small number of patient colon tumor tissues.
Journal ArticleDOI
Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (6946-6951) 10.1073/pnas.1002422107)
Sanford J. Silverman,Allegra A. Petti,Nikolai Slavov,Lance Parsons,Ryan Briehof,Stephan Y. Thiberge,Daniel Zenklusen,Saumil J. Gandhi,Daniel R. Larson,Robert H. Singer,David Botstein +10 more