Saverio Bettuzzi

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: To the authors' knowledge, this is the first study showing that GTCs are safe and very effective for treating premalignant lesions before CaP develops and International Prostate Symptom Score and quality of life scores of G TCs-treated men with coexistent benign prostate hyperplasia improved, reaching statistical significance in the case of International Pro prostate symptom Scores.

TL;DR: Molecular classification, based on gene expression, may enhance the available prognostic tools for prostate tumors and could be correlated to differentiation grade and local invasiveness classification systems in 72.2 and 83.3% of the cases.

TL;DR: CLU gene expression might play a crucial role in prostate tumorigenesis by exerting differential biological effects on normal versus tumor cells through differential processing of CLU isoforms in the two cell systems.