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Scott C. Miller

Researcher at University of Utah

Publications -  259
Citations -  8243

Scott C. Miller is an academic researcher from University of Utah. The author has contributed to research in topics: Cancellous bone & Bone remodeling. The author has an hindex of 52, co-authored 258 publications receiving 7925 citations. Previous affiliations of Scott C. Miller include University of Nebraska Medical Center & Harvard University.

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Expression and signal transduction of calcium-sensing receptors in cartilage and bone.

TL;DR: In this paper, the effects of CaR agonists on signal transduction in chondrogenic and osteogenic cell lines were investigated and the results supported the concept that changes in [Ca 21 ] may couple to signaling pathways important in skeletal metabolism.
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Bone-targeting macromolecular therapeutics.

TL;DR: Bone-targeting drug delivery systems based on water-soluble polymers can specifically direct candidate drugs to bone thereby reducing side effects due to non-specific tissue interactions.
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Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems

TL;DR: Four polymeric bone-targeting conjugates were synthesized based on poly(ethylene glycol) (PEG) and poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) and indicated that these novel delivery systems could specifically accumulate in the bone tissue.
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Alterations in bone characteristics associated with glycemic control in adolescents with type 1 diabetes mellitus.

TL;DR: Altered bone mineral acquisition in adolescents with type 1 DM may limit peak bone mass acquisition and increase the risk of osteoporosis in later life.
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Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis

TL;DR: A novel pH-sensitive drug delivery system based on an N-(2-hydroxypropyl)methacrylamide copolymer (P-Dex) provides a unique method for selective targeting of glucocorticoids to inflamed joints which may potentially reduce systemic side effects.