S
Scott M. Grundy
Researcher at University of Texas Southwestern Medical Center
Publications - 849
Citations - 246629
Scott M. Grundy is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 187, co-authored 841 publications receiving 231821 citations. Previous affiliations of Scott M. Grundy include University of California, San Francisco & University of California, Davis.
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Advancing drug therapy of the metabolic syndrome
TL;DR: The metabolic syndrome — a group of factors that raise the risk of cardiovascular disease and type 2 diabetes — is increasingly common and how might the challenges of developing improved therapies to normalize these risk factors be approached?
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Serum lipoproteins in psoriasis.
TL;DR: Gandhi et al. as mentioned in this paper found an increase in the total fats in the serum of patients with psoriasis, which was not confirmed by equally competent observers, and they were not on special diets, nor were standard S/ 0-12 and standard Sf 1-JfiO lipoprotein levels in the general population* and in psoría patients.
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Statins for all
TL;DR: An alternate approach to cholesterol management is to establish cholesterol goals for secondary and primary prevention, which allows more flexibility in treatment by taking advantage of lifestyle therapies and various drugs and their doses to attain defined goals.
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Activation of a cryptic splice-site in intron 24 leads to the formation of apolipoprotein B-27.6
TL;DR: The characterization of the effects of a T-->C transition in the splice-site at +2 of intron 24 previously reported by Talmud et al. is reported, indicating that this splICE-site mutation leads to an activation of a downstream cryptic spliced-site within intron24, causing an insertion of 40 bases of introns 24 sequences into the mature RNA.
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7. Management of hypertriglyceridemic patients: B. Dietary management of hypertriglyceridemic patients
Rafael Carmena,Scott M. Grundy +1 more
TL;DR: Consumption of fish, which contain high amounts of n-3 long-chain fatty acids, may have a therapeutic benefit in patients with hypertriglyceridemia and is recommended as a source of fat in their diet.