S
Scott M. Grundy
Researcher at University of Texas Southwestern Medical Center
Publications - 849
Citations - 246629
Scott M. Grundy is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 187, co-authored 841 publications receiving 231821 citations. Previous affiliations of Scott M. Grundy include University of California, San Francisco & University of California, Davis.
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Journal ArticleDOI
Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary.
Scott M. Grundy,James I. Cleeman,Stephen R. Daniels,Karen A. Donato,Robert H. Eckel,Barry A. Franklin,David Gordon,Ronald M. Krauss,Peter J. Savage,Sidney C. Smith,John A. Spertus,Fernando Costa +11 more
TL;DR: The metabolic risk factors consist of atherogenic dyslipidemia (elevated triglycerides and apolipoprotein B, small LDL particles, and low HDL cholesterol [HDL-C] concentrations), elevated blood pressure, elevated plasma glucose, a prothrombotic state, and a proinflammatory state as mentioned in this paper.
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Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels.
Jonathan Cohen,Alexander Pertsemlidis,Saleemah Fahmi,Sophie Esmail,Gloria Lena Vega,Scott M. Grundy,Helen H. Hobbs +6 more
TL;DR: A genetic architecture for LDL-C levels that does not conform to current models for quantitative traits is revealed and it is indicated that a significant fraction of genetic variance in HDL-C is due to multiple alleles with modest effects that are present at low frequencies in the population.
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Principles for National and Regional Guidelines on Cardiovascular Disease Prevention A Scientific Statement From the World Heart and Stroke Forum
Sidney C. Smith,Rod Jackson,Thomas A. Pearson,Valentin Fuster,Salim Yusuf,O. Faergeman,David A. Wood,Michael H. Alderman,John Horgan,Philip Home,Marilyn Hunn,Scott M. Grundy +11 more
TL;DR: The recommendations in this report focus on clinical management of patients with established CVD and those at high risk; however, it is essential that each country include a societal approach to CVD prevention.
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Obesity, metabolic syndrome, and coronary atherosclerosis
TL;DR: The relationship between obesity and coronary atherosclerosis (and coronary heart disease [CHD]) has been a subject of some dispute for many years and multivariate analysis of Framingham data strongly suggests that most of the relationship between body weight and CHD risk is mediated through the standard, major risk factors.
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Guide to Preventive Cardiology for Women
Lori Mosca,Scott M. Grundy,Debra R. Judelson,Kathleen B. King,Marian C. Limacher,Suzanne Oparil,Richard C. Pasternak,Thomas A. Pearson,Rita F. Redberg,Sidney C. Smith,Mary Winston,Stanley Zinberg +11 more
TL;DR: The purpose of this statement is to highlight risk factor management strategies that are appropriate for women with a broad range of CHD risk, and to highlight clinicians are missing opportunities to prevent CHD.