S
Scott M. Grundy
Researcher at University of Texas Southwestern Medical Center
Publications - 849
Citations - 246629
Scott M. Grundy is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 187, co-authored 841 publications receiving 231821 citations. Previous affiliations of Scott M. Grundy include University of California, San Francisco & University of California, Davis.
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Journal ArticleDOI
The effect of diabetic control on very low-density lipoprotein-Triglyceride metabolism in patients with type II diabetes mellitus and marked hypertriglyceridemia
Fredrick L. Dunn,Fredrick L. Dunn,Fredrick L. Dunn,Philip Raskin,Philip Raskin,Philip Raskin,David W. Bilheimer,David W. Bilheimer,David W. Bilheimer,Scott M. Grundy,Scott M. Grundy,Scott M. Grundy +11 more
TL;DR: Failure of diabetic treatment to restore VLDL-TG kinetic parameters to normal suggests that the hypertriglyceridemia was due not only to diabetes mellitus but also to an additional abnormality affecting lipoprotein metabolism.
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Independent associations between metabolic syndrome, diabetes mellitus and atherosclerosis: observations from the Dallas Heart Study:
Karen Chen,Jason B. Lindsey,Amit Khera,James A. de Lemos,Colby Ayers,Abhinav Goyal,Gloria Lena Vega,Sabina A. Murphy,Scott M. Grundy,Darren K. McGuire +9 more
TL;DR: Both MetS and DM are independently associated with an increased prevalence of atherosclerosis, with the highest observed prevalence in subjects with both DM and MetS.
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Influence of plasma triglycerides on lipoprotein patterns in normal subjects and in patients with coronary artery disease
E. Glen Richards,E. Glen Richards,Scott M. Grundy,Scott M. Grundy,Kenneth H. Cooper,Kenneth H. Cooper +5 more
TL;DR: The results indicate that the lipoprotein pattern, including lipoproteins concentrations and particle sizes, is sensitive to concentrations of plasma triglycerides even when the latter are within the normal range.
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Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations.
Ralph V. Shohet,Gloria L. Vega,Azam Anwar,Joaquin E. Cigarroa,Scott M. Grundy,Scott M. Grundy,Jonathan Cohen +6 more
TL;DR: The data indicate that a primary decrease in hepatic lipase activity of as much as 30% does not influence susceptibility to CAD in white men.
Journal ArticleDOI
Hypertriglyceridemia: mechanisms, clinical significance, and treatment.
TL;DR: The association between hypertriglyceridemia and coronary heart disease is explored followed by a discussion of the mechanisms of the disorder and guidelines on patient evaluation and treatment.