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Seamus J. Martin

Researcher at Trinity College, Dublin

Publications -  214
Citations -  54934

Seamus J. Martin is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 88, co-authored 205 publications receiving 48661 citations. Previous affiliations of Seamus J. Martin include National University of Ireland & University of Leicester.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Lorenzo Galluzzi, +186 more
TL;DR: The Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.
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Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

TL;DR: It is shown that PS externalization is an early and widespread event during apoptosis of a variety of murine and human cell types, regardless of the initiating stimulus, and precedes several other events normally associated with this mode of cell death.
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Suppression of TNF-α-Induced Apoptosis by NF-κB

TL;DR: In this paper, the sensitivity and kinetics of TNF-α-induced apoptosis were shown to be enhanced in a number of cell types expressing a dominant negative IkappaBalpha (Ikappa-BalphaM).