Sebastian Thrun

Bio: Sebastian Thrun is an academic researcher from Stanford University. The author has contributed to research in topics: Mobile robot & Robot. The author has an hindex of 146, co-authored 434 publications receiving 98124 citations. Previous affiliations of Sebastian Thrun include University of Pittsburgh & ETH Zurich.

Real-time identification and localization of body parts from depth images

Abstract: We deal with the problem of detecting and identifying body parts in depth images at video frame rates. Our solution involves a novel interest point detector for mesh and range data that is particularly well suited for analyzing human shape. The interest points, which are based on identifying geodesic extrema on the surface mesh, coincide with salient points of the body, which can be classified as, e.g., hand, foot or head using local shape descriptors. Our approach also provides a natural way of estimating a 3D orientation vector for a given interest point. This can be used to normalize the local shape descriptors to simplify the classification problem as well as to directly estimate the orientation of body parts in space. Experiments involving ground truth labels acquired via an active motion capture system show that our interest points in conjunction with a boosted patch classifier are significantly better in detecting body parts in depth images than state-of-the-art sliding-window based detectors.

Pearl: A Mobile Robotic Assistant for the Elderly

Abstract: The Nursebot project is a multi-disciplinary, multi-university effort aimed at developing mobile robotic assistants for the elderly. In this paper, we describe one such robot, Pearl. Pearl has two primary functions: (i) reminding people about routine activities such as eating, drinking, taking medicine, and using the bathroom, and (ii) guiding them through their environments. We provide a brief overview of the hardware platform, and we sketch the major software systems that enable Pearl to perform its two main functions. A prototype version of Pearl has been completely built, with all software implemented, and preliminary testing has been done at the Longwood Retirement Community in Oakmont, PA.

A Noise‐aware Filter for Real‐time Depth Upsampling

Abstract: A new generation of active 3D range sensors, such as time-of-flight cameras, enables recording of full-frame depth maps at video frame rate. Unfortunately, the captured data are typically starkly contaminated by noise and the sensors feature only a rather limited image resolution. We therefore present a pipeline to enhance the quality and increase the spatial resolution of range data in real-time by upsampling the range information with the data from a high resolution video camera. Our algorithm is an adaptive multi-lateral upsampling filter that takes into account the inherent noisy nature of real-time depth data. Thus, we can greatly improve reconstruction quality, boost the resolution of the data to that of the video sensor, and prevent unwanted artifacts like texture copy into geometry. Our technique has been crafted to achieve improvement in depth map quality while maintaining high computational efficiency for a real-time application. By implementing our approach on the GPU, the creation of a real-time 3D camera with video camera resolution is feasible.

Particle filters in robotics

Abstract: In recent years, particle filters have solved several hard perceptual problems in robotics. Early successes of particle filters were limited to low-dimensional estimation problems, such as the problem of robot localization in environments with known maps. More recently, researchers have begun exploiting structural properties of robotic domains that have led to successful particle filter applications in spaces with as many as 100,000 dimensions. The fact that every model--no mater how detailed--fails to capture the full complexity of even the most simple robotic environments has lead to specific tricks and techniques essential for the success of particle filters in robotic domains. This article surveys some of these recent innovations, and provides pointers to in-depth articles on the use of particle filters in robotics.

Spoken dialogue management using probabilistic reasoning

Abstract: Spoken dialogue managers have benefited from using stochastic planners such as Markov Decision Processes (MDPs). However, so far, MDPs do not handle well noisy and ambiguous speech utterances. We use a Partially Observable Markov Decision Process (POMDP)-style approach to generate dialogue strategies by inverting the notion of dialogue state; the state represents the user's intentions, rather than the system state. We demonstrate that under the same noisy conditions, a POMDP dialogue manager makes fewer mistakes than an MDP dialogue manager. Furthermore, as the quality of speech recognition degrades, the POMDP dialogue manager automatically adjusts the policy.

Deep Learning

Abstract: Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and videogames. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models. Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors.

Latent dirichlet allocation

Abstract: We describe latent Dirichlet allocation (LDA), a generative probabilistic model for collections of discrete data such as text corpora. LDA is a three-level hierarchical Bayesian model, in which each item of a collection is modeled as a finite mixture over an underlying set of topics. Each topic is, in turn, modeled as an infinite mixture over an underlying set of topic probabilities. In the context of text modeling, the topic probabilities provide an explicit representation of a document. We present efficient approximate inference techniques based on variational methods and an EM algorithm for empirical Bayes parameter estimation. We report results in document modeling, text classification, and collaborative filtering, comparing to a mixture of unigrams model and the probabilistic LSI model.

Latent Dirichlet Allocation

Abstract: We propose a generative model for text and other collections of discrete data that generalizes or improves on several previous models including naive Bayes/unigram, mixture of unigrams [6], and Hof-mann's aspect model, also known as probabilistic latent semantic indexing (pLSI) [3]. In the context of text modeling, our model posits that each document is generated as a mixture of topics, where the continuous-valued mixture proportions are distributed as a latent Dirichlet random variable. Inference and learning are carried out efficiently via variational algorithms. We present empirical results on applications of this model to problems in text modeling, collaborative filtering, and text classification.

Data Mining: Practical Machine Learning Tools and Techniques

Abstract: Data Mining: Practical Machine Learning Tools and Techniques offers a thorough grounding in machine learning concepts as well as practical advice on applying machine learning tools and techniques in real-world data mining situations. This highly anticipated third edition of the most acclaimed work on data mining and machine learning will teach you everything you need to know about preparing inputs, interpreting outputs, evaluating results, and the algorithmic methods at the heart of successful data mining. Thorough updates reflect the technical changes and modernizations that have taken place in the field since the last edition, including new material on Data Transformations, Ensemble Learning, Massive Data Sets, Multi-instance Learning, plus a new version of the popular Weka machine learning software developed by the authors. Witten, Frank, and Hall include both tried-and-true techniques of today as well as methods at the leading edge of contemporary research. *Provides a thorough grounding in machine learning concepts as well as practical advice on applying the tools and techniques to your data mining projects *Offers concrete tips and techniques for performance improvement that work by transforming the input or output in machine learning methods *Includes downloadable Weka software toolkit, a collection of machine learning algorithms for data mining tasks-in an updated, interactive interface. Algorithms in toolkit cover: data pre-processing, classification, regression, clustering, association rules, visualization

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。