Author
Sebastião J. Formosinho
Other affiliations: Royal Institution, Catholic University of Portugal
Bio: Sebastião J. Formosinho is an academic researcher from University of Coimbra. The author has contributed to research in topics: Uranyl & Bond order. The author has an hindex of 26, co-authored 148 publications receiving 3891 citations. Previous affiliations of Sebastião J. Formosinho include Royal Institution & Catholic University of Portugal.
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the intrinsic processes and mechanisms of proton transfer in relation to the nature of the intramolecular hydrogen bond ring are reviewed. But the authors focus on the intrinsic process and not the mechanisms of transfer.
Abstract: Excited-state intramolecular proton transfer reactions are reviewed. Special emphasis is given to the intrinsic processes and to the mechanisms of proton transfers in relation to the nature of the intramolecular hydrogen bond ring.
647 citations
TL;DR: Theoretical models that have been proposed and applied to proton transfer reactions are reviewed in this paper, where simple models, like the Eigen model, Marcus theory and the intersecting state model, are applied to excited-state intermolecular proton transfers.
Abstract: Theoretical models that have been proposed and applied to proton transfer reactions are reviewed in this work. Simple models, like the Eigen model, Marcus theory and the intersecting state model, are applied to excited-state intermolecular proton transfers. The kinetics and thermodynamics of proton transfers occuring in the singlet states of aromatic molecules with OH, NH3+, NH2 and CO substituents are reviewed.
507 citations
TL;DR: In this paper, photoacoustic calorimetry was used to measure the quantum yields of singlet molecular oxygen production by the triplet states of tetraphenylporphyrin (TPP), ZnTPP and CuTPP in toluene, yielding values of 0.67 0.14, 0.68 0.19 and 0.03 0.07 quantum yield.
Abstract: Photoacoustic calorimetry was used to measure the quantum yields of singlet molecular oxygen production by the triplet states of tetraphenylporphyrin (TPP), ZnTPP and CuTPP in toluene, yielding values of 0.67 0.14, 0.68 0.19 and 0.03 0.01, respectively. We show that a novel dichlorophenyl derivative of ZnTPP is capable of singlet-oxygen production with a 0.90 0.07 quantum yield. The synthesis and characterisation of a new photostable chlorin with high absorptivity in the red that is capable of singlet-oxygen production with 0.54 0.06 quantum yield is described. Our results suggest that chlorinated chlorins may be interesting new sensitisers for photodynamic therapy.
209 citations
TL;DR: A completely automated method to improve single linkage hierarchical cluster analysis (HCA), based on a self-consistent outlier reduction approach, followed by the building-up of a descriptive function, which allows to define natural clusters.
181 citations
TL;DR: This work uses both model dependent and independent techniques to assess the difference between dissolution profiles in which ibuprofen, in the form of uncoated pellets, is used as a model drug.
171 citations
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TL;DR: In this article, the photophysical properties of singlet molecular oxygen and of the photosensitizers used in its generation are examined and compared, with particular focus on its role in wastewater treatment, fine chemical synthesis, and photodynamic therapy.
2,382 citations
TL;DR: Polanyi is at pains to expunge what he believes to be the false notion contained in the contemporary view of science which treats it as an object and basically impersonal discipline.
Abstract: The Study of Man. By Michael Polanyi. Price, $1.75. Pp. 102. University of Chicago Press, 5750 Ellis Ave., Chicago 37, 1959. One subtitle to Polanyi's challenging and fascinating book might be The Evolution and Natural History of Error , for Polanyi is at pains to expunge what he believes to be the false notion contained in the contemporary view of science which treats it as an object and basically impersonal discipline. According to Polanyi not only is this a radical and important error, but it is harmful to the objectives of science itself. Another subtitle could be Farewell to Detachment , for in place of cold objectivity he develops the idea that science is necessarily intensely personal. It is a human endeavor and human point of view which cannot be divorced from nor uprooted out of the human matrix from which it arises and in which it works. For a good while
2,248 citations
TL;DR: This paper presents a meta-modelling study of the response of the immune system to chemotherapy and its applications in the context of central nervous system disorders.
Abstract: Sasidharan Swarnalatha Lucky,†,§ Khee Chee Soo,‡ and Yong Zhang*,†,§,∥ †NUS Graduate School for Integrative Sciences & Engineering (NGS), National University of Singapore, Singapore, Singapore 117456 ‡Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore 169610 Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore 117576 College of Chemistry and Life Sciences, Zhejiang Normal University, Zhejiang, P. R. China 321004
2,194 citations
TL;DR: Proton-coupled electron transfer is an important mechanism for charge transfer in a wide variety of systems including biology- and materials-oriented venues and several are reviewed.
Abstract: ▪ Abstract Proton-coupled electron transfer (PCET) is an important mechanism for charge transfer in a wide variety of systems including biology- and materials-oriented venues. We review several are...
2,182 citations
01 Jan 1995
TL;DR: In this paper, the authors propose a method to improve the quality of the data collected by the data collection system. But it is difficult to implement and time consuming and computationally expensive.
Abstract: 本文对国际科学计量学杂志《Ｓｃｉｅｎｔｏｍｅｔｒｉｃｓ》１９７９－１９９１年的研究论文内容、栏目、作者及国别和编委及国别作了计量分析，揭示出科学计量学研究的重点、活动的中心及发展趋势，说明了学科带头人在发展科学计量学这门新兴学科中的作用。
1,636 citations