S
Sébastien Colette
Researcher at Université catholique de Louvain
Publications - 25
Citations - 1136
Sébastien Colette is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Endometriosis & Proinflammatory cytokine. The author has an hindex of 16, co-authored 25 publications receiving 966 citations. Previous affiliations of Sébastien Colette include Cliniques Universitaires Saint-Luc.
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Journal ArticleDOI
Endometriomas as a Possible Cause of Reduced Ovarian Reserve in Women With Endometriosis
Michio Kitajima,Sylvie Defrère,Marie-Madeleine Dolmans,Sébastien Colette,Jean Squifflet,Anne Van Langendonckt,Jacques Donnez +6 more
TL;DR: Endometriotic cyst formation and associated structural tissue alterations in apparently normal ovarian cortex may be a cause of reduced ovarian reserve and early diagnosis and intervention may be beneficial in women with endometriomas to protect their ovarian function.
Journal ArticleDOI
Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis.
Reinaldo González-Ramos,Anne Van Langendonckt,Sylvie Defrère,Jean-Christophe Lousse,Sébastien Colette,Luigi Devoto,Jacques Donnez +6 more
TL;DR: In this article, the role of NF-κB in the pathogenesis of endometriosis has been evaluated using a literature search conducted in PubMed to identify all relevant citations, highlighting the important role of NGF in the pathwayophysiology of Endometria.
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Potential involvement of iron in the pathogenesis of peritoneal endometriosis
Sylvie Defrère,Jean-Christophe Lousse,Reinaldo González-Ramos,Sébastien Colette,Jacques Donnez,A. Van Langendonckt +5 more
TL;DR: Excess iron accumulation can result in toxicity and may be one of the factors contributing to the development of endometriosis, so treatment with an iron chelator could be beneficial in endometiosis patients to prevent iron overload in the pelvic cavity, thereby diminishing its deleterious effect.
Journal ArticleDOI
Peritoneal endometriosis is an inflammatory disease.
Jean-Christophe Lousse,Anne Van Langendonckt,Sylvie Defrère,Reinaldo González Ramos,Sébastien Colette,Jacques Donnez +5 more
TL;DR: The respective involvement and potential molecular interactions of iron, nuclear factor-kappa B and prostaglandins in the pathogenesis of endometriosis are explored and discussed and the key role of peritoneal macrophages is emphasized and potential therapeutic targets are examined.
Journal ArticleDOI
Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid
Jean-Christophe Lousse,Sylvie Defrère,Anne Van Langendonckt,Jeremie Gras,Reinaldo González-Ramos,Sébastien Colette,Jacques Donnez +6 more
TL;DR: Iron storage is statistically significantly increased in peritoneal macrophages of patients with endometriosis and correlates with iron overload in peritonal fluid and the potential implications of iron accumulation inPeritoneal Macrophages in case of endometiosis are discussed.