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Seema Sharma

Bio: Seema Sharma is an academic researcher from Magadh University. The author has contributed to research in topics: Silver nanoparticle & Nanoparticle. The author has an hindex of 8, co-authored 20 publications receiving 1429 citations. Previous affiliations of Seema Sharma include University of Manchester & University of Delhi.

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TL;DR: The various phytochemicals present within the ocimum plant result in effective reduction of silver salts to nanoparticles but their chemical framework is also effective at wrapping around the nanoparticles to provide excellent robustness against agglomeration.

585 citations

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TL;DR: Water-soluble antioxidative agents like ascorbic acids further seem to be responsible for the reduction of AgNPs, which show good antimicrobial activity against common pathogens.
Abstract: A single-step environmental friendly approach is employed to synthesize silver nanoparticles. The biomolecules found in plants induce the reduction of Ag+ ions from silver nitrate to silver nanoparticles (AgNPs). UV-visible spectrum of the aqueous medium containing silver ions demonstrated a peak at 425 nm corresponding to the plasmon absorbance of silver nanoparticles. Transmission electron microscopy (TEM) showed the formation of well-dispersed silver nanoparticles in the range of 5–20 nm. X-ray diffraction (XRD) spectrum of the AgNPs exhibited 2θ values corresponding to the silver nanocrystal. The process of reduction is extracellular and fast which may lead to the development of easy biosynthesis of silver nanoparticles. Plants during glycolysis produce a large amount of H+ ions along with NAD which acts as a strong redoxing agent; this seems to be responsible for the formation of AgNPs. Water-soluble antioxidative agents like ascorbic acids further seem to be responsible for the reduction of AgNPs. These AgNPs produced show good antimicrobial activity against common pathogens.

525 citations

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TL;DR: In this article, the synthesis of green-silver nanoparticles using extracts of Ananas comosus reducing aqueous silver nitrate has been demonstrated using extracts from pineapple juice, which is a green chemistry approach that intercom nects nanotechnology and plant biotechnology.
Abstract: The biosynthesis of nanoparticles has been proposed as a cost effective and environmental friendly alternative to chemical and physical methods. Plant mediated synthesis of nanoparticles is a green chemistry approach that intercom nects nanotechnology and plant biotechnology. In the present study, synthesis of silver nanoparticles (AgNPs) or (Green-Silver) has been demonstrated using extracts of Ananas comosus reducing aqueous silver nitrate. The AgNPs were characterized by Ultraviolet-Visible (UV-vis) Spectrometer, Energy Dispersive X-ray Analysis (EDAX), Selected Area Diffraction Pattern (SAED) and High Resolution Transmission Electron Microscopy (HRTEM). TEM micrographs showed spherical particles with an average size of 12 nm. The XRD pattern showed the characteristic Bragg peaks of (111), (200), (220) and (311) facets of the face center cubic (fcc) silver nanoparticles and confirmed that these nanoparticles are crystalline in nature. The different types of antioxidants presented in the pineapple juice synergistically reduce the Ag metal ions, as each antioxidant is unique in terms of its structure and antioxidant function. The re- action process was simple for formation of silver nanoparticles and AgNPs presented in the aqueous medium were quite stable, even up to 4 months of incubation. This work proved the capability of using biomaterial towards the synthesis of silver nanoparticle, by adopting the principles of green chemistry.

232 citations

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TL;DR: In this paper, a simple and eco-friendly biosynthesis of silver nanoparticles using Pomegranate peel extract as the reducing agent was presented, where the reaction process was simple for the formation of highly stable silver and gold nanoparticles at room temperature by using the biowaste of the fruit.
Abstract: We present a simple and eco-friendly biosynthesis of silver nanoparticles using Pomegranate peel extract as the reducing agent. Peel extract of Pomegranate was challenged with silver nitrate (AgNO3) and chloroauric acid (HAuCl4) solution for the production of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs), respectively. The reaction process was simple for the formation of highly stable silver and gold nanoparticles at room temperature by using the biowaste of the fruit. The morphology and crystalline phase of the NPs were determined from UV-Vis spectroscopy, transmission electron microscopy (TEM), selected area electron diffraction (SAED) and X-ray diffraction (XRD) spectra. TEM studies showed that the average particle size of silver nanoparticles were 5 ±1.5 nm whereas the gold nanoparticles were found to be 10 ±1.5 nm. An effort has been also been made to understand the possible involved mechanism for the biosynthesis of the NPs. Presumably biosynthetic products or reduced cofactors play an important role in the reduction of respective salts to nanoparticles. Copyright © 2012 VBRI press.

122 citations

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TL;DR: In this article, a mixture of lead-free NKN and Na 0.5 K 0.4 NbO 3 (NKN) was used to obtain a saturation polarization (P sat ) of 30μC/cm 2, remanent polarization ( P r ) of 27μC /cm 2 and coercive field ( E c ) of 1.0 kV/mm.
Abstract: Lead-free Na 0.5 K 0.5 NbO 3 (NKN) and Na 0.475 K 0.475 Li 0.05 NbO 3 (NKLN) ceramics doped with CuO were prepared by the mixed oxide route. The powders were calcined at 850–930 °C and sintered at 850–1100 °C. Small additions of CuO reduced the sintering temperature and increased the density to 96% theoretical. Cu first appears to enter the A site then the B site. In NKLN the orthorhombic–tetragonal and tetragonal–cubic phase transitions are approximately 150 °C lower and 50 °C higher, respectively than in NKN. With increasing addition of Cu to NKN and NKLN the remanent polarization ( P r ) increased and coercive field ( E c ) decreased. NKLN prepared with 0.4 wt% CuO exhibited a saturation polarization ( P sat ) of 30 μC/cm 2 , remanent polarization ( P r ) of 27 μC/cm 2 and coercive field ( E c ) of 1.0 kV/mm. CuO caused the NKLN ceramics to harden considerably; the mechanical quality factor ( Q m ) increased from 50 to 260, d 33 ∼ 285 and piezoelectric coupling factors were >0.4.

82 citations


Cited by
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7,335 citations

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TL;DR: Most of the plants used in metal nanoparticle synthesis are shown in this article, and the advantages of using plant and plant-derived materials for biosynthesis of metal nanoparticles have interested researchers to investigate mechanisms of metal ions uptake and bioreduction by plants, and to understand the possible mechanism of nanoparticle formation in plants.

2,424 citations

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TL;DR: A comprehensive view on the mechanism of action, production, applications in the medical field, and health and environmental concerns that are allegedly caused due to these nanoparticles is provided in this paper.
Abstract: Silver nanoparticles are nanoparticles of silver which are in the range of 1 and 100 nm in size. Silver nanoparticles have unique properties which help in molecular diagnostics, in therapies, as well as in devices that are used in several medical procedures. The major methods used for silver nanoparticle synthesis are the physical and chemical methods. The problem with the chemical and physical methods is that the synthesis is expensive and can also have toxic substances absorbed onto them. To overcome this, the biological method provides a feasible alternative. The major biological systems involved in this are bacteria, fungi, and plant extracts. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications. In most of the therapeutic applications, it is the antimicrobial property that is being majorly explored, though the anti-inflammatory property has its fair share of applications. Though silver nanoparticles are rampantly used in many medical procedures and devices as well as in various biological fields, they have their drawbacks due to nanotoxicity. This review provides a comprehensive view on the mechanism of action, production, applications in the medical field, and the health and environmental concerns that are allegedly caused due to these nanoparticles. The focus is on effective and efficient synthesis of silver nanoparticles while exploring their various prospective applications besides trying to understand the current scenario in the debates on the toxicity concerns these nanoparticles pose.

1,852 citations

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TL;DR: The methods of making nanoparticles using plant extracts are reviewed, methods of particle characterization are reviewed and potential applications of the particles in medicine are discussed.

1,706 citations