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Sehamuddin Galadari

Researcher at New York University Abu Dhabi

Publications -  74
Citations -  9722

Sehamuddin Galadari is an academic researcher from New York University Abu Dhabi. The author has contributed to research in topics: Ceramide & Apoptosis. The author has an hindex of 31, co-authored 70 publications receiving 7864 citations. Previous affiliations of Sehamuddin Galadari include United Arab Emirates University & Medical University of South Carolina.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Reactive oxygen species and cancer paradox: To promote or to suppress?

Sehamuddin Galadari, +4 more
- 01 Mar 2017 - 
TL;DR: This review focuses on the current understanding of the tumor promoting and the tumor suppressive functions of ROS, and highlights the potential mechanism(s) involved, and sheds light on a very novel and an actively growing field of ROS‐dependent cell death mechanism referred to as ferroptosis.
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Rapid reactive oxygen species (ros) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in l929 cells

Faisal Thayyullathil, +4 more
- 15 Nov 2008 - 
TL;DR: It is shown for the first time that curcumin-induced rapid ROS generation causes the release of apoptosis inducing factor (AIF) from the mitochondria to the cytosol and nucleus, hence, leading to caspase 3-independent apoptosis.
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Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.

Cungui Mao, +5 more
- 13 Jul 2001 - 
TL;DR: The identification and cloning of a cDNA encoding for a novel human alkaline ceramidase (aPHC) that hydrolyzes phytoceramide selectively is reported, the first mammalian alkaline ceramicase to be identified as being specific for the hydrolysis of phytOCeramide.