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Sepideh Khoee

Bio: Sepideh Khoee is an academic researcher from University of Tehran. The author has contributed to research in topics: Drug delivery & Nanoparticle. The author has an hindex of 28, co-authored 135 publications receiving 2336 citations. Previous affiliations of Sepideh Khoee include University of Isfahan & Isfahan University of Technology.


Papers
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Journal ArticleDOI
TL;DR: The proposed electrode has fast response time, and long term stability (more than 2 months), and was used to determine the concentration of lead ions in waste water and black tea samples.

122 citations

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TL;DR: It was found that the encapsulation efficiencies of penicillin-G enhanced up to 76.8% with the increase in Span and Tween contents, and the in vitro drug release profiles exhibited a significant burst release, followed by a lag phase of little or no release.

114 citations

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TL;DR: In this paper, the authors investigated the in situ encapsulation of n-hexadecane as a phase change material (PCM) with a polymethyl methacrylate (PMMA) shell through miniemulsion polymerization.
Abstract: The aim of this study is to investigate the in situ encapsulation of n-hexadecane as a phase change material (PCM) with a polymethyl methacrylate (PMMA) shell through miniemulsion polymerization. n-Hexadecane (HD) and methyl methacrylate (MMA) form dispersed minidroplets in the aqueous phase, whereas PMMA is immiscible with n-hexadecane and separates through polymerization to produce hollow polymer particles filled with n-hexadecane. Different HD:MMA ratios and ethylene glycol dimethacrylate (EGDMA) as a cross-linking agent were considered to optimize the encapsulation process. A new approach by using novel equations from DSC, DLS, and microscopy analyses were developed to estimate shell thickness and the extent of contribution of MMA in the formation of the nanocapsules, pure polymeric particles, and also the void fraction of nanocapsules. It was found that the weight fractions of pure polymeric particles for the prepared samples were 12–17 wt %, and the shell thickness of the nanocapsules was about 12 n...

99 citations

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TL;DR: Evidence is provided that nanoparticles loaded hydrogels could be used for extended delivery of loteprednol etabonate and perhaps other drugs.

73 citations

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TL;DR: In this paper, the authors investigated the use of multifunctional nanoparticles that designed with a Nano-graphene oxide (NGO) sheet functionalized with magnetic poly (lactic-co-glycolic acid) (PLGA) and was used for glioma targeting delivery of radiosensitizing 5-iodo-2-deoxyuridine (IUdR).

68 citations


Cited by
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Journal ArticleDOI
TL;DR: This work aims to provide a comprehensive overview of electrospun nanofibers, including the principle, methods, materials, and applications, and highlights the most relevant and recent advances related to the applications by focusing on the most representative examples.
Abstract: Electrospinning is a versatile and viable technique for generating ultrathin fibers. Remarkable progress has been made with regard to the development of electrospinning methods and engineering of electrospun nanofibers to suit or enable various applications. We aim to provide a comprehensive overview of electrospinning, including the principle, methods, materials, and applications. We begin with a brief introduction to the early history of electrospinning, followed by discussion of its principle and typical apparatus. We then discuss its renaissance over the past two decades as a powerful technology for the production of nanofibers with diversified compositions, structures, and properties. Afterward, we discuss the applications of electrospun nanofibers, including their use as "smart" mats, filtration membranes, catalytic supports, energy harvesting/conversion/storage components, and photonic and electronic devices, as well as biomedical scaffolds. We highlight the most relevant and recent advances related to the applications of electrospun nanofibers by focusing on the most representative examples. We also offer perspectives on the challenges, opportunities, and new directions for future development. At the end, we discuss approaches to the scale-up production of electrospun nanofibers and briefly discuss various types of commercial products based on electrospun nanofibers that have found widespread use in our everyday life.

2,289 citations

Journal ArticleDOI
TL;DR: A comparative analysis is given of the size, zeta-potential, dispersion pH, shell thickness, encapsulation efficiency, active substance release, stability and in vivo and in vitro pharmacological performances, which allows establishing criteria for selecting a method for preparation of nanocapsules according to its advantages, limitations and behaviours as a drug carrier.

1,462 citations

Journal ArticleDOI
TL;DR: In this paper, a review of the preparation of polymer nanoparticles and the crucial parameters involved in techniques designed to obtain the desired properties is presented, and the choice of method depends on a number of factors, such as particle size, particle size distribution, area of application, etc.

1,393 citations

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TL;DR: This text is a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA.
Abstract: The text consists of two sections, one for those studying or practicing diagnostic radiology, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia.

1,359 citations

Journal ArticleDOI
TL;DR: In this article, the authors focus on the application of various phase change materials based on their thermophysical properties, in particular, the melting point, thermal energy storage density and thermal conductivity of the organic, inorganic and eutectic phases.

813 citations