Sergey Nurk

TL;DR: SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies.

TL;DR: The T2T-Y consortium presented the complete 62,460,029 base pair sequence of a human Y chromosome from the HG002 genome (T2T -Y) that corrects multiple errors in GRCh38-Y and adds over 30 million base pairs of sequence to the reference, revealing the complete ampliconic structures of TSPY, DAZ, and RBMY gene families; 41 additional protein-coding genes, mostly from the T SPY family; and an alternating pattern of human satellite 1 and 3 blocks in the heterochromatic Yq12 region as mentioned in this paper .

TL;DR: The Telomere-to-Telomere consortium recently assembled the first truly complete sequence of a human genome, but to resolve the most complex repeats, this project relied on manual integration of ultra-long Oxford Nanopore sequencing reads with a high-resolution assembly graph built from long, accurate PacBio HiFi reads.

TL;DR: In this article , the authors constructed 1:1 unambiguous alignments spanning high-identity segmental duplications across 102 human haplotypes and compared the pattern of SNVs between unique and duplicated regions.