S
Seung Hun Lee
Researcher at University of Ulsan
Publications - 253
Citations - 5359
Seung Hun Lee is an academic researcher from University of Ulsan. The author has contributed to research in topics: Osteoporosis & Bone mineral. The author has an hindex of 35, co-authored 231 publications receiving 4621 citations. Previous affiliations of Seung Hun Lee include Kyungpook National University Hospital & Yonsei University.
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Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.
Mao-Qiang Man,Yutaka Hatano,Seung Hun Lee,M. Man,Sandra Chang,Kenneth R. Feingold,Donald Y.M. Leung,Walter M. Holleran,Yoshikazu Uchida,Peter M. Elias +9 more
TL;DR: Here, multiple Ox challenges to normal murine skin produce a chronic Th2-like HR, with multiple features of human AD, which could prove useful for evaluating both pathogenic mechanisms and potential therapies for AD.
Journal ArticleDOI
An Update of the Defensive Barrier Function of Skin
TL;DR: The recent achievements of skin researchers focusing on the functions of the epidermal permeability barrier and their importance in skin disease, such as atopic dermatitis and psoriasis are introduced.
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery
Se Kyoo Jeong,Hyun Jeong Kim,Jong Kyung Youm,Sung Ku Ahn,Eung Ho Choi,Myung Hyun Sohn,Kyu-Earn Kim,Jeong Hee Hong,Dong Min Shin,Seung Hun Lee +9 more
TL;DR: In this article, the effects of both allergens on the epidermal barrier function as well as on the Epidermal calcium gradient were investigated, and it was shown that when applied on the barrier-disrupted site, increased protease activities in the epIDERmis and delayed barrier recovery and lamellar body secretion in murine skin.
Journal ArticleDOI
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery
Se Kyoo Jeong,Hyun Jeong Kim,Jong Kyung Youm,Sung Ku Ahn,Eung Ho Choi,Myung Hyun Sohn,Kyu-Earn Kim,Jeong Hee Hong,Dong Min Shin,Seung Hun Lee +9 more
TL;DR: It is suggested that allergens with protease activity can influence the epidermal permeability barrier homeostasis through PAR-2 activation and consequent modulation of the calcium ions in skin.
Journal ArticleDOI
Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement.
Seung Phil Hong,Min Jung Kim,Min Young Jung,Hyerin Jeon,Jawoong Goo,Sung Ku Ahn,Seung Hun Lee,Peter M. Elias,Eung Ho Choi +8 more
TL;DR: The results provide new insights into the mechanisms whereby low-dose UVB comprises effective therapy for AD and suggest that the beneficial effect of low- dose UVB depends, at least in part, on activation of the cutaneous vitamin D system.