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Sezgi Arpag
Researcher at Old Dominion University
Publications - 4
Citations - 38
Sezgi Arpag is an academic researcher from Old Dominion University. The author has contributed to research in topics: Genetic enhancement & Gene delivery. The author has an hindex of 2, co-authored 4 publications receiving 27 citations.
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Journal ArticleDOI
IL-12 Gene Electrotransfer Triggers a Change in Immune Response within Mouse Tumors.
TL;DR: A basic understanding of the sequence of immune activity following pIL-12 GET is suggested and it is illuminated that adjuvant immunotherapy can have a positive influence on the host immune response to cancer.
Journal ArticleDOI
Secretion of proteins and antibody fragments from transiently transfected endothelial progenitor cells.
Loree C. Heller,Reynald Thinard,Melanie Chevalier,Sezgi Arpag,Yu Jing,Ruth Greferath,Richard Heller,Claude Nicolau +7 more
TL;DR: It is demonstrated that EPC transfection by electroporation with plasmids encoding the reporter protein GFP or an anti‐β‐amyloid antibody fragment (Fab) leads to secretion of each protein.
Journal ArticleDOI
Reduction of plasmid vector backbone length enhances reporter gene expression.
Carly Boye,Sezgi Arpag,Michael Francis,Scott DeClemente,Aislin West,Richard Heller,Anna Bulysheva +6 more
TL;DR: In this article, a 2-fold reduction in plasmid vector backbone size, disproportionately enhanced gene expression levels more than 10-fold in rat tenocytes in vitro and rat myocardium in vivo, while improvements in delivery to the skin were moderate.
Journal ArticleDOI
Cardioporation enhances myocardial gene expression in rat heart.
Carly Boye,Sezgi Arpag,Nina Burcus,Cathryn Lundberg,Scott DeClemente,Richard Heller,Michael Francis,Anna Bulysheva +7 more
TL;DR: By using a surface monopolar electrode, optimized pulsing conditions and reducing vector size, the study was able to prevent ventricular fibrillation, increase survival, reduce tissue damage, and significantly increase gene expression levels.