S
Shaf Keshavjee
Researcher at University Health Network
Publications - 927
Citations - 36797
Shaf Keshavjee is an academic researcher from University Health Network. The author has contributed to research in topics: Lung transplantation & Transplantation. The author has an hindex of 87, co-authored 814 publications receiving 31548 citations. Previous affiliations of Shaf Keshavjee include University of Toronto & University of Pennsylvania.
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Journal ArticleDOI
A consensus document for the selection of lung transplant candidates: 2014-An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation
David Weill,Christian Benden,Paul A. Corris,John H. Dark,R. Duane Davis,Shaf Keshavjee,David J. Lederer,Michael J. Mulligan,G. Alexander Patterson,Lianne G. Singer,Greg Snell,Geert Verleden,Martin R. Zamora,Allan R. Glanville +13 more
TL;DR: Recommendations include discussions not present in previous ISHLT guidelines, including lung allocation scores, bridging to transplant with mechanical circulatory and ventilator support, and expanded indications for lung transplantation.
Journal ArticleDOI
International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation.
Jonathan B. Orens,Marc Estenne,Selim M. Arcasoy,John V. Conte,Paul A. Corris,Jim J. Egan,Thomas M. Egan,Shaf Keshavjee,Christiane Knoop,Robert M. Kotloff,Fernando J. Martinez,Steven D. Nathan,Scott M. Palmer,A. Patterson,Lianne G. Singer,Gregory I Snell,Sean M. Studer,Jean-Luc Vachiery,Allan R. Glanville +18 more
TL;DR: This update to the international guidelines is based primarily on a consensus of opinion rendered by experts in the field and should not be considered to be hard and fast rules.
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Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation
Marcelo Cypel,Jonathan C. Yeung,Mingyao Liu,Masaki Anraku,Fengshi Chen,W. Karolak,Masaaki Sato,Jane Laratta,Sassan Azad,Mindy Madonik,Chung-Wai Chow,Cecilia Chaparro,Michael Hutcheon,Lianne G. Singer,Arthur S. Slutsky,Kazuhiro Yasufuku,Marc de Perrot,Andrew Pierre,Thomas K. Waddell,Shaf Keshavjee +19 more
TL;DR: Transplantation of high-risk donor lungs that were physiologically stable during 4 hours of ex vivo perfusion led to results similar to those obtained with conventionally selected lungs.
Journal ArticleDOI
Ischemia-reperfusion-induced lung injury.
TL;DR: Better understanding of the mechanisms of ischemia-reperfusion injury, improvements in the technique of lung preservation, and the development of a new preservation solution specifically for the lung have been associated with a reduction in the incidence of primary graft failure from approximately 30 to 15% or less.
Journal ArticleDOI
Injurious Mechanical Ventilation and End-Organ Epithelial Cell Apoptosis and Organ Dysfunction in an Experimental Model of Acute Respiratory Distress Syndrome
Yumiko Imai,Jean Parodo,Osamu Kajikawa,Marc de Perrot,Stefan Fischer,Vern Edwards,Ernest Cutz,Mingyao Liu,Shaf Keshavjee,Thomas R. Martin,John C. Marshall,V. Marco Ranieri,Arthur S. Slutsky +12 more
TL;DR: In this paper, the authors examined the hypothesis that an injurious ventilatory strategy may lead to end-organ epithelial cell apoptosis and organ dysfunction, and showed that a lung protection strategy led to increased rates of epithelialcell apoptosis in the kidney.