There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

A diverse spectrum of technology drivers such as improved thermal barriers, higher efficiency thermoelectric energy conversion, phase-change memory, heat-assisted magnetic recording, thermal management of nanoscale electronics, and nanoparticles for thermal medical therapies are motivating studies of the applied physics of thermal transport at the nanoscale. This review emphasizes developments in experiment, theory, and computation in the past ten years and summarizes the present status of the field. Interfaces become increasingly important on small length scales. Research during the past decade has extended studies of interfaces between simple metals and inorganic crystals to interfaces with molecular materials and liquids with systematic control of interface chemistry and physics. At separations on the order of ∼1 nm, the science of radiative transport through nanoscale gaps overlaps with thermal conduction by the coupling of electronic and vibrational excitations across weakly bonded or rough interface...

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Nanoscale thermal transport. II. 2003–2012

The smart grid concept continues to evolve and various methods have been developed to enhance the energy efficiency of the electricity infrastructure. Demand Response (DR) is considered as the most cost-effective and reliable solution for the smoothing of the demand curve, when the system is under stress. DR refers to a procedure that is applied to motivate changes in the customers' power consumption habits, in response to incentives regarding the electricity prices. In this paper, we provide a comprehensive review of various DR schemes and programs, based on the motivations offered to the consumers to participate in the program. We classify the proposed DR schemes according to their control mechanism, to the motivations offered to reduce the power consumption and to the DR decision variable. We also present various optimization models for the optimal control of the DR strategies that have been proposed so far. These models are also categorized, based on the target of the optimization procedure. The key aspects that should be considered in the optimization problem are the system's constraints and the computational complexity of the applied optimization algorithm.

A Survey on Demand Response Programs in Smart Grids: Pricing Methods and Optimization Algorithms

Introduction to heat transfer

Many intelligent transportation systems are multiagent systems, i.e., both the traffic participants and the subsystems within the transportation infrastructure can be modeled as interacting agents. The use of AI-based methods to achieve coordination among the different agents systems can provide greater safety over transportation systems containing only human-operated vehicles, and also improve the system efficiency in terms of traffic throughput, sensing range, and enabling collaborative tasks. However, increased autonomy makes the transportation infrastructure vulnerable to compromised vehicular agents or infrastructure. This paper proposes a new framework by embedding the trust authority into transportation infrastructure to systematically quantify the trustworthiness of agents using an epistemic logic known as subjective logic. In this paper, we make the following novel contributions: (i) We propose a framework for using the quantified trustworthiness of agents to enable trust-aware coordination and control. (ii) We demonstrate how to synthesize trust-aware controllers using an approach based on reinforcement learning. (iii) We comprehensively analyze an autonomous intersection management (AIM) case study and develop a trust-aware version called AIM-Trust that leads to lower accident rates in scenarios consisting of a mixture of trusted and untrusted agents.

Trust-aware Control for Intelligent Transportation Systems

Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide; however, there is no specific vaccine against MPXV. In this study, therefore, we employed computational approaches to design a multi-epitope vaccine against MPXV. Initially, cytotoxic T lymphocyte (CTL), helper T lymphocyte (HTL), linear B lymphocytes (LBL) epitopes were predicted from the cell surface-binding protein and envelope protein A28 homolog, both of which play essential roles in MPXV pathogenesis. All of the predicted epitopes were evaluated using key parameters. A total of 7 CTL, 4 HTL, and 5 LBL epitopes were chosen and combined with appropriate linkers and adjuvant to construct a multi-epitope vaccine. The CTL and HTL epitopes of the vaccine construct cover 95.57% of the worldwide population. The designed vaccine construct was found to be highly antigenic, non-allergenic, soluble, and to have acceptable physicochemical properties. The 3D structure of the vaccine and its potential interaction with Toll-Like receptor-4 (TLR4) were predicted. Molecular dynamics (MD) simulation confirmed the vaccine’s high stability in complex with TLR4. Finally, codon adaptation and in silico cloning confirmed the high expression rate of the vaccine constructs in strain K12 of Escherichia coli (E. coli). These findings are very encouraging; however, in vitro and animal studies are needed to ensure the potency and safety of this vaccine candidate.

/pdf/in-silico-design-and-immunoinformatics-analysis-of-a-24xrlhpj.pdf

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

This paper introduces a new current-based cell timing analyzer, called CGTA, which has a higher performance than existing logic cell timing analysis tools. CGTA relies on a compact lookup table storing the output current gain (sensitivity) of every logic cell as a function of its input voltage and output load. The current gain values are subsequently used by the timing calculator to produce the output current value as a function of the applied input voltage. This current and the output load then uniquely determine the output voltage value. Therefore, CGTA is capable of efficiently and accurately computing the output voltage waveform of a logic cell, which has been subjected to an arbitrary noisy input voltage waveform. Experimental results are presented to assess the quality of CGTA compared to other existing approaches.

https://www.aspdac.com/aspdac2006/archives/pdf/1C-2.pdf

CGTA: current gain-based timing analysis for logic cells

Memory accounts for a considerable portion of the total power budget and area of digital systems. Furthermore, it is typically the performance bottleneck of the processing units. Therefore, it is critical to optimize the memory with respect to the product of power, area, and delay (PAD). We propose a hybrid cell assignment method based on multi-sized and dual-Vth SRAM cells which improves the PAD cost function by 34% compared to the conventional cell assignment. We also utilize the sizing of SRAM cells for minimizing the Data Retention Voltage (DRV), and voltages for the read and write operations in the SRAM array. Experimental results in a 32nm technology show that combining the proposed hybrid cell assignment and the cell sizing methods can lower PAD by up to 41% when compared to the conventional cell design and assignment.

Hybrid Cell Assignment and Sizing for Power, Area, Delay Product Optimization of SRAM Arrays

Many intelligent transportation systems are multi-agent systems, i.e., both the traffic participants and the subsystems within the transportation infrastructure can be modeled as interacting agents. The use of AI-based methods to achieve coordination among the different agents systems can provide greater safety over transportation systems containing only human-operated vehicles, and also improve the system efficiency in terms of traffic throughput, sensing range, and enabling collaborative tasks. However, increased autonomy makes the transportation infrastructure vulnerable to compromised vehicular agents or infrastructure. This paper proposes a new framework by embedding the trust authority into transportation infrastructure to systematically quantify the trustworthiness of agents using an epistemic logic known as subjective logic. In this paper, we make the following novel contributions: (i) We propose a framework for using the quantified trustworthiness of agents to enable trust-aware coordination and control. (ii) We demonstrate how to synthesize trust-aware controllers using an approach based on reinforcement learning. (iii) We comprehensively analyze an autonomous intersection management (AIM) case study and develop a trust-aware version called AIM-Trust that leads to lower accident rates in scenarios consisting of a mixture of trusted and untrusted agents.

Shahin Nazarian

Papers

Trust-aware Control for Intelligent Transportation Systems

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

CGTA: current gain-based timing analysis for logic cells

Hybrid Cell Assignment and Sizing for Power, Area, Delay Product Optimization of SRAM Arrays

Trust-aware Control for Intelligent Transportation Systems