S
Shailesh Kumar Patel
Researcher at Indian Veterinary Research Institute
Publications - 60
Citations - 1470
Shailesh Kumar Patel is an academic researcher from Indian Veterinary Research Institute. The author has contributed to research in topics: Medicine & Pandemic. The author has an hindex of 15, co-authored 43 publications receiving 803 citations.
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Journal ArticleDOI
SARS-CoV-2 jumping the species barrier: Zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus.
Kuldeep Dhama,Shailesh Kumar Patel,Khan Sharun,Mamta Pathak,Ruchi Tiwari,Mohd Iqbal Yatoo,Yashpal Singh Malik,Ranjit Sah,Ali A. Rabaan,Parmod Kumar Panwar,Karam Pal Singh,Izabela Michalak,Wanpen Chaicumpa,Dayron F. Martinez-Pulgarin,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales +15 more
TL;DR: A comprehensive overview of COVID-19 and SARS-CoV-2 is presented, with emphasis on the role of animals and their jumping the cross-species barriers, experiences learned from Sars- and MERS-CoVs, zoonotic links, and spillover events, transmission to humans and rapid spread.
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An update on SARS-CoV-2/COVID-19 with particular reference to its clinical pathology, pathogenesis, immunopathology and mitigation strategies.
Kuldeep Dhama,Shailesh Kumar Patel,Mamta Pathak,Mohd Iqbal Yatoo,Ruchi Tiwari,Yashpal Singh Malik,Rajendra Singh,Ranjit Sah,Ali A. Rabaan,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales +10 more
TL;DR: An overview of this virus and the disease with a particular focus on SARS-CoV-2/COVID-19 clinical pathology, pathogenesis, and immunopathology, along with recent research developments is presented.
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Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19.
Khan Sharun,Kuldeep Dhama,Shailesh Kumar Patel,Mamta Pathak,Ruchi Tiwari,Bhoj Raj Singh,Ranjit Sah,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales,Hakan Leblebicioglu +9 more
TL;DR: The recent report by Caly et al., describing the antiviral potential of ivermectin against the severe acute respiratory syndrome coronavirus 2 in vitro arrive to the agenda of potential candidates for COVID-19 treatment, gave hope to the researchers who are screening for drugs that can be repurposed for treating the Coronavirus Disease 2019 treatment.
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Coronavirus disease pandemic (Covid-19): Challenges and a global perspective
Yashpal Singh Malik,Naveen Kumar,Shubhankar Sircar,Rahul Kaushik,Sudipta Bhat,Kuldeep Dhama,Parakriti Gupta,Kapil Goyal,Mini P Singh,Ujjala Ghoshal,Mohamed E. El Zowalaty,Mohamed E. El Zowalaty,Vinodh Kumar O. R,Mohd Iqbal Yatoo,Ruchi Tiwari,Mamta Pathak,Shailesh Kumar Patel,Ranjit Sah,Alfonso J. Rodriguez-Morales,Balasubramanian Ganesh,Prashant Kumar,Raj Kumar Singh +21 more
TL;DR: It is speculated that the efficient replication and transmission of SARS-CoV-2 might be due to the high-density basic amino acid residues, preferably positioned in close proximity at both the furin-like cleavage sites (S1/S2 and S2′) within the spike protein.
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SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic.
Ali A. Rabaan,Shamsah H. Al-Ahmed,Ranjit Sah,Ruchi Tiwari,Mohd Iqbal Yatoo,Shailesh Kumar Patel,Mamta Pathak,Yashpal Singh Malik,Kuldeep Dhama,Karam Pal Singh,D. Katterine Bonilla-Aldana,Shafiul Haque,Dayron F. Martinez-Pulgarin,Alfonso J. Rodriguez-Morales,Hakan Leblebicioglu +14 more
TL;DR: The underlying molecular organization and phylogenetic analysis of the coronaviruses, including the SARS-CoV-2, and recent advances in diagnosis and vaccine development are described, focusing mainly on developing potential therapeutic options that can be explored to manage this pandemic virus infection, which would help in valid countering of COVID-19.