Sharifzadeh Gh.R.

Bio: Sharifzadeh Gh.R. is an academic researcher from Birjand University of Medical Sciences. The author has contributed to research in topics: Risk factor & Infant mortality. The author has an hindex of 9, co-authored 33 publications receiving 267 citations.

The epidemiology of Tuberculosis in Birjand (1996-2006)

Abstract: Background and Aim: Tuberculosis (TB) covers a wide spectrum of clinical diseases caused by mycobacterium tuberculosis. Each second, one individual is infected with TB; every four seconds one develops it; and every 10 seconds one patient loses his or her life because of the disease. Ten million new cases of TB and 3 million deaths by this infection are reported annually. Regarding the importance of the disease in our country, particularly its high prevalence in the bordering provinces of the country, the present study was designed and carried out to assess the epidemiology of TB in Birjand. Materials and Methods: This research was an analytical and descriptive study covering all patients who had referred to the center of TB control in Birjand during one decade (1996-2006). Data collection was done through a questionnaire aptly designed for the study. The obtained data was analysed by means of SPSS software, statistical tests including χ and t-test were used at the significant level of P<0.05. Results: Totally, 840 cases were diagnosed; 42.6% of them were males, 96.1% Iranians, and 41% were villagers. Mean age of the patients was 48.9±21.6 years. Prevalence of the disease varied between 14.6% (the least) and 40.6% (the most) per 100000 people .Out of the total cases, %70 (588 patients) were pulmonary tuberculosis and %30 (252) were extrapulmonary; the most common of which were lymph node, spinal column, and pleural TB. Regarding types of the disease 90.5% were new cases, 8% were relapses, 0.6% treatment failure, 0.2% resistant; 83.7% were treated with a 6 month and 16.3% with an 8 month regimen. This research didn't show any significant difference with respect to sex, nationality, and habitation. Mean age of developing the disease in males was significantly higher than females’ (P=0.003). The age of the patients was also significantly higher in extrapulmonary compared to pulmonary TB (P<0.001). Conclusion: Regarding the high prevalence of TB incidence in Birjand it is necessary to follow up case finding, prevention and treatment of TB in the health-care system of the city so that an appropriate condition for the decrease of TB incidence would be provided.

To identify the risk factors in prematurity birth in birjand, iran: a case–control study

Abstract: s / 1 Iranian Journal of Epidemiology 2011; 7(3): 1-5.

Health-risk assessment related to the fluoride, nitrate, and nitrite in the drinking water in the Sanandaj, Kurdistan County, Iran

Abstract: The concentration of fluoride and nitrate in groundwater is usually higher than that of surface water. The main objective of this study was to estimate the health-risk assessment associated with fl...

HIV HBV and HCV Coinfection Prevalence in Iran--A Systematic Review and Meta-Analysis.

Abstract: Background worldwide, hepatitis C and B virus infections (HCV and HCV), are the two most common coinfections with human immunodeficiency virus (HIV) and has become a major threat to the survival of HIV-infected persons. The review aimed to estimate the prevalence of HIV, HBV, HCV, HIV/HCV and HIV/HBV and triple coinfections in different subpopulations in Iran. Method Following PRISMA guidelines, we conducted a systematic review and meta-analysis of reports on prevalence of HIV, HBV, HCV and HIV coinfections in different subpopulations in Iran. We systematically reviewed the literature to identify eligible studies from January 1996 to March 2012 in English or Persian/Farsi databases. We extracted the prevalence of HIV antibodies (diagnosed by Elisa confirmed with Western Blot test), HCV antibodies and HBsAg (with confirmatory laboratory test) as the main primary outcome. We reported the prevalence of the three infections and coinfections as point and 95% confidence intervals. Findings HIV prevalence varied from %0.00 (95% CI: 0.00–0.003) in the general population to %17.25 (95% CI: 2.94–31.57) in people who inject drugs (PWID). HBV prevalence ranged from % 0.00 (95% CI: 0.00–7.87) in health care workers to % 30.9 (95% CI: 27.88–33.92) in PWID. HCV prevalence ranged from %0.19 (95% CI: 0.00–0.66) in health care workers to %51.46 (95% CI: 34.30–68.62) in PWID. The coinfection of HIV/HBV and also HIV/HCV in the general population and in health care workers was zero, while the most common coinfections were HIV/HCV (10.95%), HIV/HBV (1.88%) and triple infections (1.25%) in PWID. Conclusions We found that PWID are severely and disproportionately affected by HIV and the other two infections, HCV and HBV. Screenings of such coinfections need to be reinforced to prevent new infections and also reduce further transmission in their community and to others.

Metabolic syndrome and its correlated factors in an urban population in South West of Iran

Abstract: This study was designed to assess the prevalence of metabolic syndrome and its correlated factors in an urban population in Ahvaz. This descriptive analytical study performed with random cluster sampling method in 6 health centers in Ahvaz. In each selected center, 55 households were randomly selected. A questionnaire included: age, sex, marital status, ethnicity, education level, family history of diabetes (DM), Hypertension (HTN) and obesity, smoking and parity and previous history of gestational diabetes Mellitus in women were filled for each person. Blood pressure, weight, height, body mass index (BMI), abdominal and waist circumference were measured in each participant. Fasting blood glucose (FBS), serum total cholesterol, triglyceride and high density lipoprotein (HDL) level were measured in fasting blood sample. The mean age of all participants was 42.27 ± 14 years (44.2 ± 14.26 years in men and 40.5 ± 13.5 in women). From total 912 participant, 434(47.2%) were men and 478(52.8%) women. Prevalence of metabolic syndrome based on ATPIII criteria (update2005) was 22.8% (15.9% in men and 29.1% in women) that showed significant difference (P = 0.0001). Prevalence of each component of MS in studied population was: 29.4% for abdominal obesity, 40.7% for high TG level, 40.2% for low HDL, 15.4% for hypertension and 37.8% for abnormal FBS. Among these factor, age of patients, BMI, sex had significant differences between persons with or without Ms (P = 0.0001). Ethnicity (Arab or Persian), cigarette smoking and family history of diabetes mellitus, hypertension and obesity, marital statues, education level, parity and previous history of GDM in women showed no significant differences between persons with MS and without MS. Metabolic syndrome has high prevalence in our population and its prevalence increases with increasing age and BMI. Women are at higher risk for metabolic syndrome than men.