S
Shasha Rao
Researcher at University of South Australia
Publications - 38
Citations - 1502
Shasha Rao is an academic researcher from University of South Australia. The author has contributed to research in topics: Drug delivery & Bioavailability. The author has an hindex of 22, co-authored 38 publications receiving 1238 citations.
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Journal ArticleDOI
Targeted drug delivery using genetically engineered diatom biosilica
Bahman Delalat,Vonda C. Sheppard,Soraya Rasi Ghaemi,Shasha Rao,Clive A. Prestidge,Gordon McPhee,Mary-Louise Rogers,Jacqueline F. Donoghue,Jacqueline F. Donoghue,Vinochani Pillay,Vinochani Pillay,Terrance Grant Johns,Terrance Grant Johns,Nils Kröger,Nils Kröger,Nicolas H. Voelcker +15 more
TL;DR: Genetically engineered biosilica frustules may be used as versatile 'backpacks' for the targeted delivery of poorly water-soluble anticancer drugs to tumour sites, and treatment with the same biosilicas leads to tumours growth regression in a subcutaneous mouse xenograft model of neuroblastoma.
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Prodrug and nanomedicine approaches for the delivery of the camptothecin analogue SN38
TL;DR: This review summarizes the recent advances for the delivery of SN38 with a focus on macromolecular prodrugs and nanomedicines.
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Transforming Lipid-Based Oral Drug Delivery Systems into Solid Dosage Forms: An Overview of Solid Carriers, Physicochemical Properties, and Biopharmaceutical Performance
TL;DR: This review describes the types of pharmaceutical grade excipients used as solid carriers and the current state of knowledge on the liquid-to-solid conversion approaches, and details are primarily focused on the solid-state physicochemical properties and redispersion capacity of various dry lipid-based formulations.
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Intestine-on-a-Chip Microfluidic Model for Efficient in Vitro Screening of Oral Chemotherapeutic Uptake
Kyall J. Pocock,Ludivine C. Delon,Vaskor Bala,Shasha Rao,Craig Priest,Clive A. Prestidge,Benjamin Thierry +6 more
TL;DR: A microfluidic-based intestine-on-a-chip (IOAC) model has the potential to provide new insight into the structure-permeability relationship for lipophilic prodrugs and is envisaged to also be applicable to nanoparticle and biological entities.
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Polymer-lipid hybrid systems: merging the benefits of polymeric and lipid-based nanocarriers to improve oral drug delivery
Shasha Rao,Clive A. Prestidge +1 more
TL;DR: A review of polymer-lipid hybrid systems with a specific focus on their viability in oral drug delivery is presented in this article, focusing on their application to overcome the various biological barriers to oral drug absorption.