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Author

Shihui Ying

Bio: Shihui Ying is an academic researcher from Shanghai University. The author has contributed to research in topic(s): Iterative closest point & Image registration. The author has an hindex of 17, co-authored 64 publication(s) receiving 1232 citation(s). Previous affiliations of Shihui Ying include University of North Carolina at Chapel Hill & Xi'an Jiaotong University.


Papers
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Jun Shi1, Xiao Zheng1, Yan Li2, Qi Zhang1, Shihui Ying1 
TL;DR: Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature-learning-based algorithms for AD diagnosis.
Abstract: The accurate diagnosis of Alzheimer's disease (AD) and its early stage, i.e., mild cognitive impairment, is essential for timely treatment and possible delay of AD. Fusion of multimodal neuroimaging data, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), has shown its effectiveness for AD diagnosis. The deep polynomial networks (DPN) is a recently proposed deep learning algorithm, which performs well on both large-scale and small-size datasets. In this study, a multimodal stacked DPN (MM-SDPN) algorithm, which MM-SDPN consists of two-stage SDPNs, is proposed to fuse and learn feature representation from multimodal neuroimaging data for AD diagnosis. Specifically speaking, two SDPNs are first used to learn high-level features of MRI and PET, respectively, which are then fed to another SDPN to fuse multimodal neuroimaging information. The proposed MM-SDPN algorithm is applied to the ADNI dataset to conduct both binary classification and multiclass classification tasks. Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature-learning-based algorithms for AD diagnosis.

205 citations

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TL;DR: A novel generalized ICP algorithm based on lie group for affine registration of m-D point sets based on singular value decomposition technique, which decomposes affine transformation into three special matrices which are then constrained.
Abstract: The traditional iterative closest point (ICP) algorithm is accurate and fast for rigid point set registration but it is unable to handle affine case. This paper instead introduces a novel generalized ICP algorithm based on lie group for affine registration of m-D point sets. First, with singular value decomposition technique applied, this paper decomposes affine transformation into three special matrices which are then constrained. Then, these matrices are expressed by exponential mappings of lie group and their Taylor approximations at each iterative step of affine ICP algorithm. In this way, affine registration problem is ultimately simplified to a quadratic programming problem. By solving this quadratic problem, the new algorithm converges monotonically to a local minimum from any given initial parameters. Hence, to reach desired minimum, good initial parameters and constraints are required which are successfully estimated by independent component analysis. This new algorithm is independent of shape representation and feature extraction, and thereby it is a general framework for affine registration of m-D point sets. Experimental results demonstrate its robustness and efficiency compared with the traditional ICP algorithm and the state-of-the-art methods.

120 citations

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TL;DR: A new ICP algorithm is established, named Scale-ICP algorithm, for registration of the data sets with isotropic stretches, and a way to select the initial registrations is proposed in order to achieve global convergence for the proposed algorithm.
Abstract: In this paper, we are concerned with the registration of two 3D data sets with large-scale stretches and noises. First, by incorporating a scale factor into the standard iterative closest point (ICP) algorithm, we formulate the registration into a constraint optimization problem over a 7D nonlinear space. Then, we apply the singular value decomposition (SVD) approach to iteratively solving such optimization problem. Finally, we establish a new ICP algorithm, named Scale-ICP algorithm, for registration of the data sets with isotropic stretches. In order to achieve global convergence for the proposed algorithm, we propose a way to select the initial registrations. To demonstrate the performance and efficiency of the proposed algorithm, we give several comparative experiments between Scale-ICP algorithm and the standard ICP algorithm.

90 citations

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TL;DR: A novel approach named the scaling iterative closest point (SICP) algorithm which integrates a scale matrix with boundaries into the original ICP algorithm for scaling registration of m-D point sets is introduced.
Abstract: Point set registration is important for calibration of multiple cameras, 3D reconstruction and recognition, etc. The iterative closest point (ICP) algorithm is accurate and fast for point set registration in a same scale, but it does not handle the case with different scales. This paper instead introduces a novel approach named the scaling iterative closest point (SICP) algorithm which integrates a scale matrix with boundaries into the original ICP algorithm for scaling registration. At each iterative step of this algorithm, we set up correspondence between two m-D point sets, and then use a simple and fast iterative algorithm with the singular value decomposition (SVD) method and the properties of parabola incorporated to compute scale, rotation and translation transformations. The SICP algorithm has been proved to converge monotonically to a local minimum from any given parameters. Hence, to reach desired global minimum, good initial parameters are required which are successfully estimated in this paper by analyzing covariance matrices of point sets. The SICP algorithm is independent of shape representation and feature extraction, and thereby it is general for scaling registration of m-D point sets. Experimental results demonstrate its efficiency and accuracy compared with the standard ICP algorithm.

83 citations

Proceedings ArticleDOI

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Shaoyi Du, Nanning Zheng, Shihui Ying1, Qubo You1, Yang Wu1 
12 Nov 2007
TL;DR: This paper introduces a novel approach named the scaling iterative closest point (SICP) algorithm which integrates a scale matrix with boundaries into the original ICP algorithm for scaling registration.
Abstract: The ICP algorithm is accurate and fast for registration between two point sets in a same scale, but it doesn't handle the case with different scales. This paper instead introduces a novel approach named the scaling iterative closest point (SICP) algorithm which integrates a scale matrix with boundaries into the original ICP algorithm for scaling registration. This method uses a simple iterative algorithm with the SVD algorithm and the properties of parabola incorporated to compute the translation, rotation and scale transformations at each iterative step, and its convergence is rapid with only a few iterations. The SICP algorithm is independent of shape representation and feature extraction; thereby it is general for scaling registration. Experimental results demonstrate its robustness and fast speed compared with the standard ICP algorithm.

63 citations


Cited by
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TL;DR: This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year, to survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks.
Abstract: Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks. Concise overviews are provided of studies per application area: neuro, retinal, pulmonary, digital pathology, breast, cardiac, abdominal, musculoskeletal. We end with a summary of the current state-of-the-art, a critical discussion of open challenges and directions for future research.

5,977 citations

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TL;DR: This paper indicates how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction, and provides a starting point for people interested in experimenting and contributing to the field of deep learning for medical imaging.
Abstract: What has happened in machine learning lately, and what does it mean for the future of medical image analysis? Machine learning has witnessed a tremendous amount of attention over the last few years. The current boom started around 2009 when so-called deep artificial neural networks began outperforming other established models on a number of important benchmarks. Deep neural networks are now the state-of-the-art machine learning models across a variety of areas, from image analysis to natural language processing, and widely deployed in academia and industry. These developments have a huge potential for medical imaging technology, medical data analysis, medical diagnostics and healthcare in general, slowly being realized. We provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis. As this has become a very broad and fast expanding field we will not survey the entire landscape of applications, but put particular focus on deep learning in MRI. Our aim is threefold: (i) give a brief introduction to deep learning with pointers to core references; (ii) indicate how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction; (iii) provide a starting point for people interested in experimenting and perhaps contributing to the field of deep learning for medical imaging by pointing out good educational resources, state-of-the-art open-source code, and interesting sources of data and problems related medical imaging.

590 citations

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TL;DR: This paper provides a comprehensive survey on the application of DL, RL, and deep RL techniques in mining biological data and compares the performances of DL techniques when applied to different data sets across various application domains.
Abstract: Rapid advances in hardware-based technologies during the past decades have opened up new possibilities for life scientists to gather multimodal data in various application domains, such as omics , bioimaging , medical imaging , and (brain/body)–machine interfaces . These have generated novel opportunities for development of dedicated data-intensive machine learning techniques. In particular, recent research in deep learning (DL), reinforcement learning (RL), and their combination (deep RL) promise to revolutionize the future of artificial intelligence. The growth in computational power accompanied by faster and increased data storage, and declining computing costs have already allowed scientists in various fields to apply these techniques on data sets that were previously intractable owing to their size and complexity. This paper provides a comprehensive survey on the application of DL, RL, and deep RL techniques in mining biological data. In addition, we compare the performances of DL techniques when applied to different data sets across various application domains. Finally, we outline open issues in this challenging research area and discuss future development perspectives.

405 citations

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TL;DR: In this mini-review, the application of digital pathological image analysis using machine learning algorithms is introduced, some problems specific to such analysis are addressed, and possible solutions are proposed.
Abstract: Abundant accumulation of digital histopathological images has led to the increased demand for their analysis, such as computer-aided diagnosis using machine learning techniques. However, digital pathological images and related tasks have some issues to be considered. In this mini-review, we introduce the application of digital pathological image analysis using machine learning algorithms, address some problems specific to such analysis, and propose possible solutions.

401 citations

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TL;DR: In this article, the authors provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis, and provide a starting point for people interested in experimenting and perhaps contributing to the field of machine learning for medical imaging.
Abstract: What has happened in machine learning lately, and what does it mean for the future of medical image analysis? Machine learning has witnessed a tremendous amount of attention over the last few years. The current boom started around 2009 when so-called deep artificial neural networks began outperforming other established models on a number of important benchmarks. Deep neural networks are now the state-of-the-art machine learning models across a variety of areas, from image analysis to natural language processing, and widely deployed in academia and industry. These developments have a huge potential for medical imaging technology, medical data analysis, medical diagnostics and healthcare in general, slowly being realized. We provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis. As this has become a very broad and fast expanding field we will not survey the entire landscape of applications, but put particular focus on deep learning in MRI. Our aim is threefold: (i) give a brief introduction to deep learning with pointers to core references; (ii) indicate how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction; (iii) provide a starting point for people interested in experimenting and perhaps contributing to the field of machine learning for medical imaging by pointing out good educational resources, state-of-the-art open-source code, and interesting sources of data and problems related medical imaging.

366 citations