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Shihui Ying

Bio: Shihui Ying is an academic researcher from Shanghai University. The author has contributed to research in topics: Computer science & Iterative closest point. The author has an hindex of 17, co-authored 64 publications receiving 1232 citations. Previous affiliations of Shihui Ying include University of North Carolina at Chapel Hill & Xi'an Jiaotong University.


Papers
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Journal ArticleDOI
Jun Shi1, Xiao Zheng1, Yan Li2, Qi Zhang1, Shihui Ying1 
TL;DR: Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature-learning-based algorithms for AD diagnosis.
Abstract: The accurate diagnosis of Alzheimer's disease (AD) and its early stage, i.e., mild cognitive impairment, is essential for timely treatment and possible delay of AD. Fusion of multimodal neuroimaging data, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), has shown its effectiveness for AD diagnosis. The deep polynomial networks (DPN) is a recently proposed deep learning algorithm, which performs well on both large-scale and small-size datasets. In this study, a multimodal stacked DPN (MM-SDPN) algorithm, which MM-SDPN consists of two-stage SDPNs, is proposed to fuse and learn feature representation from multimodal neuroimaging data for AD diagnosis. Specifically speaking, two SDPNs are first used to learn high-level features of MRI and PET, respectively, which are then fed to another SDPN to fuse multimodal neuroimaging information. The proposed MM-SDPN algorithm is applied to the ADNI dataset to conduct both binary classification and multiclass classification tasks. Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature-learning-based algorithms for AD diagnosis.

315 citations

Journal ArticleDOI
TL;DR: A novel generalized ICP algorithm based on lie group for affine registration of m-D point sets based on singular value decomposition technique, which decomposes affine transformation into three special matrices which are then constrained.

149 citations

Journal ArticleDOI
TL;DR: A new ICP algorithm is established, named Scale-ICP algorithm, for registration of the data sets with isotropic stretches, and a way to select the initial registrations is proposed in order to achieve global convergence for the proposed algorithm.
Abstract: In this paper, we are concerned with the registration of two 3D data sets with large-scale stretches and noises. First, by incorporating a scale factor into the standard iterative closest point (ICP) algorithm, we formulate the registration into a constraint optimization problem over a 7D nonlinear space. Then, we apply the singular value decomposition (SVD) approach to iteratively solving such optimization problem. Finally, we establish a new ICP algorithm, named Scale-ICP algorithm, for registration of the data sets with isotropic stretches. In order to achieve global convergence for the proposed algorithm, we propose a way to select the initial registrations. To demonstrate the performance and efficiency of the proposed algorithm, we give several comparative experiments between Scale-ICP algorithm and the standard ICP algorithm.

110 citations

Journal ArticleDOI
TL;DR: This work proposes a novel residual learning-based SR algorithm for MRI, which combines both multi-scale GRL and shallow network block-based local residual learning (LRL), which works effectively in capturing high-frequency details by learning local residuals.
Abstract: Spatial resolution is one of the key parameters of magnetic resonance imaging (MRI). The image super-resolution (SR) technique offers an alternative approach to improve the spatial resolution of MRI due to its simplicity. Convolutional neural networks (CNN)-based SR algorithms have achieved state-of-the-art performance, in which the global residual learning (GRL) strategy is now commonly used due to its effectiveness for learning image details for SR. However, the partial loss of image details usually happens in a very deep network due to the degradation problem. In this work, we propose a novel residual learning-based SR algorithm for MRI, which combines both multi-scale GRL and shallow network block-based local residual learning (LRL). The proposed LRL module works effectively in capturing high-frequency details by learning local residuals. One simulated MRI dataset and two real MRI datasets have been used to evaluate our algorithm. The experimental results show that the proposed SR algorithm achieves superior performance to all of the other compared CNN-based SR algorithms in this work.

89 citations

Journal ArticleDOI
TL;DR: A novel approach named the scaling iterative closest point (SICP) algorithm which integrates a scale matrix with boundaries into the original ICP algorithm for scaling registration of m-D point sets is introduced.

89 citations


Cited by
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Journal ArticleDOI
TL;DR: This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year, to survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks.

8,730 citations

Posted Content
TL;DR: This work proposes the Learning without Forgetting method, which uses only new task data to train the network while preserving the original capabilities, and performs favorably compared to commonly used feature extraction and fine-tuning adaption techniques.
Abstract: When building a unified vision system or gradually adding new capabilities to a system, the usual assumption is that training data for all tasks is always available. However, as the number of tasks grows, storing and retraining on such data becomes infeasible. A new problem arises where we add new capabilities to a Convolutional Neural Network (CNN), but the training data for its existing capabilities are unavailable. We propose our Learning without Forgetting method, which uses only new task data to train the network while preserving the original capabilities. Our method performs favorably compared to commonly used feature extraction and fine-tuning adaption techniques and performs similarly to multitask learning that uses original task data we assume unavailable. A more surprising observation is that Learning without Forgetting may be able to replace fine-tuning with similar old and new task datasets for improved new task performance.

1,037 citations

Journal ArticleDOI
TL;DR: In this article, the authors provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis, and provide a starting point for people interested in experimenting and perhaps contributing to the field of machine learning for medical imaging.
Abstract: What has happened in machine learning lately, and what does it mean for the future of medical image analysis? Machine learning has witnessed a tremendous amount of attention over the last few years. The current boom started around 2009 when so-called deep artificial neural networks began outperforming other established models on a number of important benchmarks. Deep neural networks are now the state-of-the-art machine learning models across a variety of areas, from image analysis to natural language processing, and widely deployed in academia and industry. These developments have a huge potential for medical imaging technology, medical data analysis, medical diagnostics and healthcare in general, slowly being realized. We provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis. As this has become a very broad and fast expanding field we will not survey the entire landscape of applications, but put particular focus on deep learning in MRI. Our aim is threefold: (i) give a brief introduction to deep learning with pointers to core references; (ii) indicate how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction; (iii) provide a starting point for people interested in experimenting and perhaps contributing to the field of machine learning for medical imaging by pointing out good educational resources, state-of-the-art open-source code, and interesting sources of data and problems related medical imaging.

991 citations

Journal ArticleDOI
TL;DR: This paper provides a comprehensive survey on the application of DL, RL, and deep RL techniques in mining biological data and compares the performances of DL techniques when applied to different data sets across various application domains.
Abstract: Rapid advances in hardware-based technologies during the past decades have opened up new possibilities for life scientists to gather multimodal data in various application domains, such as omics , bioimaging , medical imaging , and (brain/body)–machine interfaces . These have generated novel opportunities for development of dedicated data-intensive machine learning techniques. In particular, recent research in deep learning (DL), reinforcement learning (RL), and their combination (deep RL) promise to revolutionize the future of artificial intelligence. The growth in computational power accompanied by faster and increased data storage, and declining computing costs have already allowed scientists in various fields to apply these techniques on data sets that were previously intractable owing to their size and complexity. This paper provides a comprehensive survey on the application of DL, RL, and deep RL techniques in mining biological data. In addition, we compare the performances of DL techniques when applied to different data sets across various application domains. Finally, we outline open issues in this challenging research area and discuss future development perspectives.

622 citations

Journal ArticleDOI
TL;DR: This paper indicates how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction, and provides a starting point for people interested in experimenting and contributing to the field of deep learning for medical imaging.
Abstract: What has happened in machine learning lately, and what does it mean for the future of medical image analysis? Machine learning has witnessed a tremendous amount of attention over the last few years. The current boom started around 2009 when so-called deep artificial neural networks began outperforming other established models on a number of important benchmarks. Deep neural networks are now the state-of-the-art machine learning models across a variety of areas, from image analysis to natural language processing, and widely deployed in academia and industry. These developments have a huge potential for medical imaging technology, medical data analysis, medical diagnostics and healthcare in general, slowly being realized. We provide a short overview of recent advances and some associated challenges in machine learning applied to medical image processing and image analysis. As this has become a very broad and fast expanding field we will not survey the entire landscape of applications, but put particular focus on deep learning in MRI. Our aim is threefold: (i) give a brief introduction to deep learning with pointers to core references; (ii) indicate how deep learning has been applied to the entire MRI processing chain, from acquisition to image retrieval, from segmentation to disease prediction; (iii) provide a starting point for people interested in experimenting and perhaps contributing to the field of deep learning for medical imaging by pointing out good educational resources, state-of-the-art open-source code, and interesting sources of data and problems related medical imaging.

590 citations