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Shijing Yue
Researcher at Heidelberg University
Publications - 10
Citations - 1156
Shijing Yue is an academic researcher from Heidelberg University. The author has contributed to research in topics: Microvesicles & Exosome. The author has an hindex of 5, co-authored 7 publications receiving 919 citations.
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Journal ArticleDOI
Toward tailored exosomes: The exosomal tetraspanin web contributes to target cell selection
TL;DR: This is the first report on the exosomal tetraspanin web contributing to target cell selection such that predictions can be made on potential targets, which will facilitate tailoring exosomes for drug delivery.
Journal ArticleDOI
Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity.
Bindhu Madhavan,Shijing Yue,Uwe Galli,Sanyukta Rana,Wolfgang Gross,Miryam Müller,Nathalia A. Giese,Holger Kalthoff,Thomas Becker,Markus W. Büchler,Margot Zöller +10 more
TL;DR: The concomitant evaluation of PaCIC and PaCa‐related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally‐invasive PaCa diagnostics.
Journal ArticleDOI
The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding
TL;DR: CD151- and Tspan8-competent tumor exosomes support matrix degradation, reprogram stroma and hematopoietic cells and drive non-metastatic ASML-CD151/Tspan8kd cells towards a motile phenotype.
Journal ArticleDOI
Tspan8 and CD151 promote metastasis by distinct mechanisms.
TL;DR: CD151 and Tspan8 coordinately promote metastasis, where Tspan6 overrides the adhesive features of CD151 by recruiting integrins out of adhesion into motility promoting complexes, and creates a path for migrating tumour cells.
Journal ArticleDOI
Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51.
TL;DR: In this paper, a Tspan8 knockout (ko) mouse was generated and compared with wild type, CD151ko and Tspan 8/CD151ko (dbko) mice.