S
Shinichi Sunagawa
Researcher at Swiss Institute of Bioinformatics
Publications - 168
Citations - 33332
Shinichi Sunagawa is an academic researcher from Swiss Institute of Bioinformatics. The author has contributed to research in topics: Metagenomics & Biology. The author has an hindex of 61, co-authored 142 publications receiving 24232 citations. Previous affiliations of Shinichi Sunagawa include European Bioinformatics Institute & University of California, Berkeley.
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Journal ArticleDOI
Richness of human gut microbiome correlates with metabolic markers
Trine Nielsen,Junjie Qin,Edi Prifti,Falk Hildebrand,Gwen Falony,Mathieu Almeida,Manimozhiyan Arumugam,Jean-Michel Batto,Sean Kennedy,Pierre Leonard,Junhua Li,Kristoffer Sølvsten Burgdorf,Niels Grarup,Torben Jørgensen,Torben Jørgensen,Torben Jørgensen,Ivan Brandslund,Henrik Nielsen,Agnieszka S. Juncker,Marcelo Bertalan,Florence Levenez,Nicolas Pons,Simon Rasmussen,Shinichi Sunagawa,Julien Tap,Sebastian Tims,Erwin G. Zoetendal,Søren Brunak,Karine Clément,Karine Clément,Joël Doré,Michiel Kleerebezem,Karsten Kristiansen,Pierre Renault,Thomas Sicheritz-Pontén,Willem M. de Vos,Willem M. de Vos,Jean-Daniel Zucker,Jean-Daniel Zucker,Jean-Daniel Zucker,Jeroen Raes,Torben Hansen,Torben Hansen,Peer Bork,Jun Wang,S. Dusko Ehrlich,Oluf Pedersen +46 more
TL;DR: The authors' classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.
Journal ArticleDOI
Structure and function of the global ocean microbiome
Shinichi Sunagawa,Luis Pedro Coelho,Samuel Chaffron,Jens Roat Kultima,Karine Labadie,Guillem Salazar,Bardya Djahanschiri,Georg Zeller,Daniel R. Mende,Adriana Alberti,Francisco M. Cornejo-Castillo,Paul I. Costea,Corinne Cruaud,Francesco d'Ovidio,Stefan Engelen,Isabel Ferrera,Josep M. Gasol,Lionel Guidi,Falk Hildebrand,Florian Kokoszka,Cyrille Lepoivre,Gipsi Lima-Mendez,Julie Poulain,Bonnie T. Poulos,Marta Royo-Llonch,Hugo Sarmento,Sara Vieira-Silva,Céline Dimier,Marc Picheral,Sarah Searson,Stefanie Kandels-Lewis,Tara Oceans Coordinators,Chris Bowler,Colomban de Vargas,Gabriel Gorsky,Nigel Grimsley,Pascal Hingamp,Daniele Iudicone,Olivier Jaillon,Fabrice Not,Hiroyuki Ogata,Stephane Pesant,Sabrina Speich,Lars Stemmann,Matthew B. Sullivan,Jean Weissenbach,Patrick Wincker,Eric Karsenti,Jeroen Raes,Silvia G. Acinas,Peer Bork +50 more
TL;DR: This work identifies ocean microbial core functionality and reveals that >73% of its abundance is shared with the human gut microbiome despite the physicochemical differences between these two ecosystems.
Journal ArticleDOI
eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences
Jaime Huerta-Cepas,Damian Szklarczyk,Damian Szklarczyk,Kristoffer Forslund,Helen Cook,Davide Heller,Davide Heller,Mathias C. Walter,Thomas Rattei,Daniel R. Mende,Shinichi Sunagawa,Michael Kuhn,Lars Juhl Jensen,Christian von Mering,Christian von Mering,Peer Bork,Peer Bork +16 more
TL;DR: The functional annotations of OGs have been expanded to also provide Gene Ontology terms, KEGG pathways and SMART/Pfam domains for each group, and eggNOG now provides pairwise orthology relationships within OGs based on analysis of phylogenetic trees.
Journal ArticleDOI
An integrated catalog of reference genes in the human gut microbiome
Junhua Li,Huijue Jia,Xianghang Cai,Huanzi Zhong,Qiang Feng,Shinichi Sunagawa,Manimozhiyan Arumugam,Jens Roat Kultima,Edi Prifti,Trine Nielsen,Agnieszka S. Juncker,Chaysavanh Manichanh,Bing Chen,Wenwei Zhang,Florence Levenez,Juan Wang,Xun Xu,Liang Xiao,Suisha Liang,Dongya Zhang,Zhaoxi Zhang,Weineng Chen,Hailong Zhao,Jumana Y. Al-Aama,Sherif Edris,Huanming Yang,Jian Wang,Torben Hansen,Henrik Nielsen,Søren Brunak,Karsten Kristiansen,Francisco Guarner,Oluf Pedersen,Joël Doré,S. Dusko Ehrlich,Peer Bork,Jun Wang +36 more
TL;DR: The integrated gene catalog (IGC) is established comprising 9,879,896 genes, which includes close-to-complete sets of genes for most gut microbes, which are also of considerably higher quality than in previous catalogs.
Journal ArticleDOI
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Kristoffer Forslund,Falk Hildebrand,Falk Hildebrand,Trine Nielsen,Gwen Falony,Gwen Falony,Shinichi Sunagawa,Edi Prifti,Sara Vieira-Silva,Sara Vieira-Silva,Valborg Gudmundsdottir,Helle Krogh Pedersen,Manimozhiyan Arumugam,Karsten Kristiansen,Anita Y. Voigt,Anita Y. Voigt,Henrik Vestergaard,Rajna Hercog,Paul I. Costea,Jens Roat Kultima,Junhua Li,Torben Jørgensen,Torben Jørgensen,Florence Levenez,Joël Doré,H. Bjørn Nielsen,Søren Brunak,Søren Brunak,Jeroen Raes,Jeroen Raes,Jeroen Raes,Torben Hansen,Torben Hansen,Jun Wang,S. Dusko Ehrlich,S. Dusko Ehrlich,Peer Bork,Oluf Pedersen +37 more
TL;DR: A unified signature of gut microbiome shifts in T2D with a depletion of butyrate-producing taxa is reported, highlighting the need to disentangle gut microbiota signatures of specific human diseases from those of medication.