S
Shirin Pourafshar
Researcher at University of Virginia
Publications - 38
Citations - 378
Shirin Pourafshar is an academic researcher from University of Virginia. The author has contributed to research in topics: Osteoporosis & Kidney disease. The author has an hindex of 9, co-authored 36 publications receiving 228 citations. Previous affiliations of Shirin Pourafshar include South Dakota State University & Florida State University.
Papers
More filters
Journal ArticleDOI
Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells
Rafaela G. Feresin,Rafaela G. Feresin,Jingwen Huang,DawnKylee S. Klarich,Yitong Zhao,Shirin Pourafshar,Bahram H. Arjmandi,Gloria Salazar +7 more
TL;DR: It is demonstrated that inhibition of Akt, p38MAPK and ERK1/2 as well as down-regulation of Nox1 by siRNA prevented senescence induced by Ang II, and that Ang II-inducedsenescence is attenuated by BL polyphenols through a Nox 1-dependent mechanism and by RB and BRB polyphenol in a NOx1-independent manner, likely by increasing the cellular antioxidant capacity.
Journal ArticleDOI
Bone-Protective Effects of Dried Plum in Postmenopausal Women: Efficacy and Possible Mechanisms.
Bahram H. Arjmandi,Sarah A. Johnson,Shirin Pourafshar,Negin Navaei,Negin Navaei,Kelli S. George,Shirin Hooshmand,Sheau C. Chai,Neda S. Akhavan +8 more
TL;DR: It is suggested that dried plum in its whole form is a promising and efficacious functional food therapy for preventing bone loss in postmenopausal women, with the potential for long-lasting bone-protective effects.
Journal ArticleDOI
Effects of daily blueberry consumption on circulating biomarkers of oxidative stress, inflammation, and antioxidant defense in postmenopausal women with pre- and stage 1-hypertension: a randomized controlled trial
Sarah A. Johnson,Rafaela G. Feresin,Negin Navaei,Arturo Figueroa,Marcus L. Elam,Neda S. Akhavan,Shirin Hooshmand,Shirin Pourafshar,Mark E. Payton,Bahram H. Arjmandi +9 more
TL;DR: Daily consumption of blueberries for 4 weeks, but not 8 weeks, attenuated a biomarker of oxidative DNA damage in pre- and stage 1-hypertensive postmenopausal women.
Journal ArticleDOI
Effects of Montmorency Tart Cherry Juice Consumption on Cardiometabolic Biomarkers in Adults with Metabolic Syndrome: A Randomized Controlled Pilot Trial
Sarah A. Johnson,Sarah A. Johnson,Negin Navaei,Negin Navaei,Shirin Pourafshar,Shirin Pourafshar,Salvador J. Jaime,Salvador J. Jaime,Neda S. Akhavan,Stacey Alvarez-Alvarado,Gabriela V. Proaño,Gabriela V. Proaño,Nicole S. Litwin,Elizabeth A. Clark,Elizabeth Foley,Kelli S. George,Marcus L. Elam,Mark E. Payton,Bahram H. Arjmandi,Arturo Figueroa,Arturo Figueroa +20 more
TL;DR: It is suggested that daily tart cherry consumption may attenuate processes involved in accelerated atherogenesis without affecting hemodynamics or arterial stiffness parameters in this population of men and women with MetS.
Journal ArticleDOI
GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans.
Joseph C. Gigliotti,Adrienne Tin,Shirin Pourafshar,Sylvia Cechova,Yves T. Wang,Sun-Sang J. Sung,Gabor Bodonyi-Kovacs,Janet V. Cross,Guang Yang,Nhu T. Nguyen,Fang Chan,Casey M. Rebholz,Bing Yu,Megan L. Grove,Morgan E. Grams,Anna Köttgen,Anna Köttgen,Robert B. Scharpf,Phillip Ruiz,Eric Boerwinkle,Josef Coresh,Thu H. Le +21 more
TL;DR: A role for the GSTM1 enzyme in the modulation of oxidative stress, inflammation, and protective metabolites in CKD is supported and treatment with Tempol rescued kidney injury in knockout mice without lowering BP.