S
Shirley Bleak
Researcher at Primary Children's Hospital
Publications - 3
Citations - 1831
Shirley Bleak is an academic researcher from Primary Children's Hospital. The author has contributed to research in topics: Subclinical infection & Antibody. The author has an hindex of 3, co-authored 3 publications receiving 1615 citations.
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Journal ArticleDOI
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.
Marilyn J. Manco-Johnson,Marilyn J. Manco-Johnson,Thomas C. Abshire,Amy D. Shapiro,Brenda Riske,Michele R. Hacker,Ray F. Kilcoyne,J. David Ingram,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,Leonard A. Valentino,W. Keith Hoots,George R. Buchanan,Donna DiMichele,Michael Recht,Deborah L Brown,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +29 more
TL;DR: Prophylaxis with recombinant factor VIII can prevent joint damage and decrease the frequency of joint and other hemorrhages in young boys with severe hemophilia A.
Journal ArticleDOI
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia.
Chengwen Li,Nattee Narkbunnam,Nattee Narkbunnam,Richard Jude Samulski,Aravind Asokan,Genlin Hu,L. J. Jacobson,M. J. Manco-Johnson,Paul E. Monahan,Marilyn J. Manco-Johnson,Brenda Riske,Ray F. Kilcoyne,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,J. David Ingram,Thomas C. Abshire,Thomas C. Abshire,Amy D. Shapiro,Michele R. Hacker,Leonard A. Valentino,W. Keith Hoots,Deborah L Brown,George R. Buchanan,Donna DiMichele,Michael Recht,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +38 more
TL;DR: The results may guide rational design of clinical trials using alternative AAV serotypes and suggest that younger patients who are given AAV gene therapy will benefit from the lower prevalence of NAbs.
Journal ArticleDOI
Prevalence of conditions associated with human immunodeficiency and hepatits virus infections among persons with haemophilia, 2001-2003
James J. Goedert,Jaime Siegel,Kay Miller,Michael M. Lederman,Alexis A. Thompson,Brittan Browning,Susan Gamerman,Kevin McRedmond,Janice S. Withycombe,Ralph A. Gruppo,Gina Stack,Jeanne M. Lusher,Linda Percy,Diane J. Nugent,Marianne McDaniel,Catherine S. Manno,Regina Butler,Amanda Wade,Anne L. Angiolillo,Naomi L.C. Luban,Christine Guelcher,Michael D. Tarantino,Suzi Greer,Joan Cox Gill,Jodie Nelson,Gilbert C. White,Michael W. Fried,Aime L. Grimsley,Donna DiMichele,Ilene Goldberg,James French,Sandra Hibner,James P. Steinberg,Steven Faust,Nigel S. Key,Vicky Hannemann,Craig M. Kessler,Anastasia E. Lee,M. Elaine Eyster,Kathryn Galli,Gillian Jenkins,Zale P. Bernstein,Linda Belling,Amy D. Shapiro,Marge Halley,Patti Noblet,Lawrence Jardine,Lori Laudenbach,Richard Lipton,Christine Pece,Cindy A. Leissinger,Cecilia V. Schmidt,Marcus E. Carr,Melinda E Nolte,Marilyn J. Manco-Johnson,Sheryl Giambartolomei,Sheldon H. Rubin,Dorine Belliveau,Louis M. Aledort,Johanna McCarthy,Richard S. Lemons,Shirley Bleak,Eric H. Kraut,Leslie Witkoff,Charles Sexauer,Felicia Kiplinger,Arthur R. Thompson,Charles Cooper,Howard A. Britton,Kathi Cobb,Hans Joachim Reimers,Judy A. Bagato,Jerry S. Powell,Muriel Herr,Karen Scott,John J. Hutter,Mary Lou Damiano,Willis H. Navarro,Jessie Roth,J. E. Palascak,Kenneth E. Sherman,Madeline Heffner,Jorge DiPaolo,Michael Lammer,Rathi V. Iyer,Prasad Matthew,Marcia Schwartz,Barbara A. Konkle,Nirmala Vijayanathan,Marion Dugdale,Donald Lilley,Keith Hoots,Deborah L Brown,M. Ullman,Anne T. Neff,Steven Klintworth,Hernan Sabio,Anita Smith,Anastasia Karafoulidou +98 more
TL;DR: The scale of hepatic and haematological disease that is likely to manifest in the adult haemophilic population during the coming years unless most of them are successfully treated for HIV‐1, HCV or both is revealed.