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Shizuo Akira

Researcher at Osaka University

Publications -  1330
Citations -  344469

Shizuo Akira is an academic researcher from Osaka University. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 261, co-authored 1308 publications receiving 320561 citations. Previous affiliations of Shizuo Akira include University of California, Berkeley & Wakayama Medical University.

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Journal ArticleDOI

Evidence for Genes in Addition to Tlr7 in the Yaa Translocation Linked with Acceleration of Systemic Lupus Erythematosus

Marie-Laure Santiago-Raber, +6 more
- 15 Jul 2008 - 
TL;DR: The results indicate that the Yaa-mediated acceleration of SLE as well as various Y-linked cellular traits cannot be explained by the Tlr7 gene duplication alone, and suggest additional contributions from other duplicated genes in the translocated X chromosome.
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Essential Immunoregulatory Role for BCAP in B Cell Development and Function

Tetsuo Yamazaki, +5 more
- 04 Mar 2002 - 
TL;DR: Findings demonstrate that BCAP plays a pivotal immunoregulatory role in B cell development and humoral immune responses.
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Influenza A Virus Polymerase Inhibits Type I Interferon Induction by Binding to Interferon β Promoter Stimulator 1

Atsushi Iwai, +8 more
- 15 Oct 2010 - 
TL;DR: It is demonstrated that the viral polymerase plays an important role for regulating host anti-viral response through the binding to IPS-1 and inhibition of IFNβ production.

Signaling to NF-kB by Toll-like receptors

Taro Kawai, +1 more
TL;DR: Recent progress in the understanding of the role of NF-kB in TLR signaling pathways is reviewed and potential implications for molecular medicine are discussed.
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FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration

Hinako Takase, +7 more
- 15 Jan 2013 - 
TL;DR: It is revealed that Thy1(+) mesenchymal cells produced FGF7 and appeared in close proximity to LPCs, implicating a role for those cells as the functional LPC niche in the regenerating liver.