Shizuo Akira

Researcher at Osaka University

Publications - 1330

Citations - 344469

Shizuo Akira is an academic researcher from Osaka University. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 261, co-authored 1308 publications receiving 320561 citations. Previous affiliations of Shizuo Akira include University of California, Berkeley & Wakayama Medical University.

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Role of the Atg9a gene in intrauterine growth and survival of fetal mice.

Takashi Kojima, +9 more

- 01 Sep 2015 -

Reproductive Biology

TL;DR: Results suggest that Atg9a(-/-) fetal mice from pregnant dams heterozygous for both knockout alleles of Atg 9a and p57(Kip2) are more susceptible to hypertensive stress than fetuses with intact autophagic machinery.

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Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease

Chongye Fang, +12 more

- 01 Mar 2019 -

Biochimica et Biophysica Acta

TL;DR: It is revealed that caffeine ameliorates non-alcoholic fatty liver disease via crosstalk between muscle IL-6 production and liver STAT3 activation and is vital for the hepatoprotective effects of caffeine in NAFLD.

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Potential link between the immune system and metabolism of nucleic acids.

Ken Ishii, +1 more

- 01 Oct 2008 -

Current Opinion in Immunology

TL;DR: During microbial infection and tissue injury, nucleic acids and their metabolites can be released from dying host cells and may modify immune responses, thereby contributing not only to the host defense, but also to the homeostatic clearance of host dying cells, or even to deleterious autoimmune diseases.

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