S
Shou Jiang
Publications - 1
Citations - 158
Shou Jiang is an academic researcher. The author has contributed to research in topics: Antiestrogen & Estrogen. The author has an hindex of 1, co-authored 1 publications receiving 155 citations.
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Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer.
Suleiman Massarweh,C. Kent Osborne,Shou Jiang,Alan E. Wakeling,Mothaffar F. Rimawi,Syed K. Mohsin,Susan G. Hilsenbeck,Rachel Schiff +7 more
TL;DR: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib significantly delayed the emergence of resistance to both estrogen deprivation and fulvestrant, but reactivation of HER-2/neu and signaling through AKT leads to tumor regrowth.