Shou-Long Deng

TL;DR: The latest advances of treatment strategy for these diseases and the application of related targeted small molecule drugs in clinical research and treatment are highlighted so as to provide reference for the treatment of female reproductive diseases.

TL;DR: The mechanism and detection methods of estrogenic endocrine disruptors, such as bisphenol A (BPA), organochlorine pesticides (OCPs), diethylstilbestrol (DES) and phthalates (PAEs), and their effects on placenta and fetal health are elaborated in order to raise concerns about the proper use of products containing EDCs during pregnancy and provide a reference for human health.

TL;DR: A novel role for GATA4 is revealed in controlling the SSC niche via the transcriptional regulation of chemokine signaling shortly after birth through deletion of Gata4 in Sertoli cells.

TL;DR: The literature data indicate that melatonin has important effects on steroidogenesis and male reproduction, and the melatonin-induced regulation of steroid hormones may differ among species.

TL;DR: Adding 0.1 mM melatonin to cryoprotectant significantly increased sperm viability and membrane integrity and decreased intracellular reactive oxygen species and lipid peroxidation damage, and melatonin decreases the ROS content of frozen–thawed human sperm.