S
Shu Zheng
Researcher at Zhejiang University
Publications - 329
Citations - 10038
Shu Zheng is an academic researcher from Zhejiang University. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 49, co-authored 310 publications receiving 7998 citations. Previous affiliations of Shu Zheng include Chinese Ministry of Education & Sanford-Burnham Institute for Medical Research.
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Journal ArticleDOI
γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer
Pin Wu,Dang Wu,Chao Ni,Jun Ye,Wuzhen Chen,Guoming Hu,Zhen Wang,Changrong Wang,Zhigang Zhang,Wenjie Xia,Zhigang Chen,Ke Wang,Tao Zhang,Jinghong Xu,Yuehua Han,Ting Zhang,Xianguo Wu,Jianwei Wang,Weihua Gong,Shu Zheng,Fuming Qiu,Jun Yan,Jian Huang +22 more
TL;DR: This study uncovers an inf-DC-γδT17-PMN-MDSC regulatory axis in human CRC that correlates MDSC-meditated immunosuppression with tumor-elicited inflammation.
Journal ArticleDOI
APC mutations in colorectal tumors with mismatch repair deficiency
Jian Huang,Nickolas Papadopoulos,Aileen McKinley,Susan M. Farrington,Lucy J. Curtis,Andrew H. Wyllie,Shu Zheng,James K V Willson,Sanford D. Markowitz,Pat Morin,Kenneth W. Kinzler,Bert Vogelstein,Bert Vogelstein,Malcolm G. Dunlop +13 more
TL;DR: It is suggested that the genetic instability that is reflected by the RER phenotype precedes, and is responsible for, APC mutation in RER large bowel tumors and have important implications for understanding the very earliest stages of neoplasia in patients with tumors deficient in mismatch repair.
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An updated Asia Pacific Consensus Recommendations on colorectal cancer screening
Joseph J.Y. Sung,Siew C. Ng,Francis K.L. Chan,Han-Mo Chiu,Hyun-Seok Kim,Takahisa Matsuda,Simon S.M. Ng,Joel Wen Liang Lau,Shu Zheng,Samuel N. Adler,Nageshwar D. Reddy,Khay Guan Yeoh,Kelvin K.F. Tsoi,Jessica Y.L. Ching,Ernst J. Kuipers,Linda Rabeneck,Graeme P. Young,Robert Steele,David A. Lieberman,Khean-Lee Goh +19 more
TL;DR: An updated list of recommendations on CRC screening is prepared, and quality of colonoscopy should be upheld and quality assurance programme should be in place to audit every aspects of CRC screening.
Journal ArticleDOI
Application of exosomes as liquid biopsy in clinical diagnosis.
TL;DR: This work investigates publication frequencies on exosomes over the past 10 years, and reviews recent clinical studies on liquid biopsy of exosome in the fields of oncology, pregnancy disorders, cardiovascular diseases, and organ transplantation.
Journal ArticleDOI
Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer.
Qiaoyi Liang,Jonathan Chiu,Ying-Xuan Chen,Yanqin Huang,Akira Higashimori,Akira Higashimori,Jing-Yuan Fang,Hassan Brim,Hassan Ashktorab,Siew C. Ng,Simon S.M. Ng,Shu Zheng,Francis K.L. Chan,Joseph J.Y. Sung,Jun Yu +14 more
TL;DR: Improved diagnostic performances of Fn alone and a simple linear combination of four bacteria showed an improved diagnostic ability compared with Fn alone, and can serve as novel noninvasive diagnostic biomarkers for colorectal cancer.