Author
Shuang Li
Other affiliations: Center for Advanced Materials
Bio: Shuang Li is an academic researcher from Nanjing Tech University. The author has contributed to research in topics: Fermentation & Rhizopus oryzae. The author has an hindex of 26, co-authored 83 publications receiving 1880 citations. Previous affiliations of Shuang Li include Center for Advanced Materials.
Topics: Fermentation, Rhizopus oryzae, Fumaric acid, Surfactin, Xylose
Papers
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TL;DR: A two-stage agitation speed control strategy, aimed at achieving high concentration, high yield and high productivity of 2,3-butanediol, was proposed.
139 citations
TL;DR: The key problems of the industrial production of microbial fumaric acid are reviewed, and various strategies, including strain improvement, morphology control, substrate choice, fermentation process and separation process, and their economical possibilities for industrial processes are discussed.
127 citations
TL;DR: The results suggested that inactivation of aldA led to a significantly improved 2,3-BD production.
Abstract: Ethanol was a major byproduct of 2,3-butanediol (2,3-BD) fermentation by Klebsiella oxytoca ME-UD-3. In order to achieve a high efficiency of 2,3-BD production, K. oxytoca mutants deficient in ethanol formation were successfully constructed by replace the aldA gene coding for aldehyde dehydrogenase with a tetracycline resistance cassette. The results suggested that inactivation of aldA led to a significantly improved 2,3-BD production. The carbon flux to 2,3-BD was enhanced by eliminating the byproducing ethanol and at the same time reducing the accumulation of another byproduct acetoin. At last, by fed-batch culturing of the mutant, the final 2,3-BD titer up to 130 g/l with the productivity of 1.63 g/l.h and the 2,3-BD yield relative to glucose of 0.48 g/g was obtained.
126 citations
TL;DR: In this paper, Bacillus subtilis BS-37 was a high-yield mutation strain; the titers of surfactin was 413 and 585 mg/l with 74.2% and 51.6% proportions of C15-surfactin, respectively.
121 citations
TL;DR: Under the optimal condition using this two-stage corn straw utilization strategy, the fumaric acid production, was up to 27.79 g/l, with the yield of 0.35 g/g, productivity of 1.33 g/L/h.
106 citations
Cited by
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TL;DR: In this paper, the potential of lignocellulosic biomass as an alternative platform to fossil resources has been analyzed and a critical review provides insights into the potential for LBS.
1,763 citations
TL;DR: In this article, a comprehensive state of the art describing the advancement in recent pretreaments, metabolic engineering approaches with special emphasis on the latest developments in consolidated biomass processing, current global scenario of bioethanol pilot plants and biorefinery concept for the production of biofuels and bioproducts.
1,369 citations
TL;DR: In this article, the potential of lignocellulosic biomass as an alternative platform to fossil resources has been analyzed and a critical review provides insights into the potential for LBS.
Abstract: The demand for petroleum dependent chemicals and materials has been increasing despite the dwindling of their fossil resources. As the dead-end of petroleum based industry has started to appear, today's modern society has to implement alternative energy and valuable chemical resources immediately. Owing to the importance of lignocellulosic biomass being the most abundant and bio-renewable biomass on earth, this critical review provides insights into the potential of lignocellulosic biomass as an alternative platform to fossil resources. In this context, over 200 value-added compounds, which can be derived from lignocellulosic biomass by various treatment methods, are presented with their references. Lignocellulosic biomass based polymers and their commercial importance are also reported mainly in the frame of these compounds. This review article aims to draw the map of lignocellulosic biomass derived chemicals and their synthetic polymers, and to reveal the scope of this map in today's modern chemical and polymer industry.
1,089 citations
TL;DR: Various strategies for efficient and economical microbial 2,3-butanediol production, including strain improvement, substrate alternation, and process development, are reviewed and compared with regard to their pros and cons.
592 citations
TL;DR: This review provides a system-level analysis of sustainable polymers and outlines key criteria with respect to the feedstocks the polymers are derived from, the manner in which thepolymers are generated, and the end-of-use options.
Abstract: The replacement of current petroleum-based plastics with sustainable alternatives is a crucial but formidable challenge for the modern society. Catalysis presents an enabling tool to facilitate the development of sustainable polymers. This review provides a system-level analysis of sustainable polymers and outlines key criteria with respect to the feedstocks the polymers are derived from, the manner in which the polymers are generated, and the end-of-use options. Specifically, we define sustainable polymers as a class of materials that are derived from renewable feedstocks and exhibit closed-loop life cycles. Among potential candidates, aliphatic polyesters and polycarbonates are promising materials due to their renewable resources and excellent biodegradability. The development of renewable monomers, the versatile synthetic routes to convert these monomers to polyesters and polycarbonate, and the different end-of-use options for these polymers are critically reviewed, with a focus on recent advances in c...
574 citations