S
Shunsuke F. Shimobayashi
Researcher at Princeton University
Publications - 20
Citations - 474
Shunsuke F. Shimobayashi is an academic researcher from Princeton University. The author has contributed to research in topics: Lipid bilayer & DNA. The author has an hindex of 8, co-authored 20 publications receiving 239 citations. Previous affiliations of Shunsuke F. Shimobayashi include Kyoto University & École Normale Supérieure.
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Journal ArticleDOI
Nucleated transcriptional condensates amplify gene expression.
Ming-Tzo Wei,Yi-Che Chang,Shunsuke F. Shimobayashi,Yongdae Shin,Yongdae Shin,Amy R. Strom,Clifford P. Brangwynne,Clifford P. Brangwynne +7 more
TL;DR: It is found that TAF15 has a unique charge distribution among the FET family members that enhances its interactions with the C-terminal domain of RNA polymerase II, suggesting that positive feedback between interacting transcriptional components drives localized phase separation to amplify gene expression.
Journal ArticleDOI
Nucleation landscape of biomolecular condensates.
Shunsuke F. Shimobayashi,Pierre Ronceray,Pierre Ronceray,David W. Sanders,Mikko Haataja,Clifford P. Brangwynne,Clifford P. Brangwynne +6 more
TL;DR: In this paper, the authors quantitatively characterize the nucleation kinetics of endogenous and biomimetic condensates in living cells, and find that key features of condensate nucleation can be quantitatively understood through a CNT-like theoretical framework.
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Direct measurement of DNA-mediated adhesion between lipid bilayers
Shunsuke F. Shimobayashi,Bortolo Matteo Mognetti,Lucia Parolini,Davide Orsi,Pietro Cicuta,L. Di Michele +5 more
TL;DR: This work focuses on the DNA-mediated multivalent interactions of a single liposome adhering to a flat supported bilayer, and simplifies geometry enables the estimate of the membrane tension induced by theDNA-mediated adhesive forces acting on theliposome.
Journal ArticleDOI
Suppression of the coffee-ring effect by sugar-assisted depinning of contact line
TL;DR: The findings show that suppressing the coffee-ring effect by adding sugar is a cost-effective, easy and nontoxic strategy for improving the pattern resolution.
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Direct observations of transition dynamics from macro- to micro-phase separation in asymmetric lipid bilayers induced by externally added glycolipids
TL;DR: First direct observations of morphological transitions from macro- to micro-phase separation using micrometer-sized asymmetric lipid vesicles exposed to externally added glycolipids (GM1:monosialotetrahexosylganglioside) are presented.