S
Sierra A. Jaramillo
Researcher at Northern Arizona University
Publications - 15
Citations - 148
Sierra A. Jaramillo is an academic researcher from Northern Arizona University. The author has contributed to research in topics: Biology & Genetically modified mouse. The author has an hindex of 3, co-authored 11 publications receiving 67 citations.
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Journal ArticleDOI
Phylogeographic, genomic, and meropenem susceptibility analysis of Burkholderia ubonensis
Erin P. Price,Derek S. Sarovich,Jessica R. Webb,Carina M. Hall,Sierra A. Jaramillo,Jason W. Sahl,Mirjam Kaestli,Mark Mayo,Glenda Harrington,Anthony L. Baker,Anthony L. Baker,Lindsay C. Sidak-Loftis,Erik W. Settles,Madeline Lummis,James M. Schupp,John D. Gillece,Apichai Tuanyok,Jeffrey H. Warner,Joseph D. Busch,Paul Keim,Paul Keim,Bart J. Currie,David M. Wagner +22 more
TL;DR: The population biology of B. ubonensis is examined, and a high degree of heterogeneity among the lipopolysaccharide O-antigen cluster loci is uncovered, with at least 35 different variants identified.
Journal ArticleDOI
Detection of SARS-CoV-2 and its S and N proteins using surface enhanced Raman spectroscopy
J.E. Sanchez,J.E. Sanchez,Sierra A. Jaramillo,Erik W. Settles,J. Jesus Velazquez Salazar,Alexander Lehr,Javier Gonzalez,Carmen Rodríguez Aranda,Hugo R. Navarro-Contreras,Marlee O. Raniere,Maxx Harvey,David M. Wagner,Andrew T. Koppisch,Robert S. Kellar,Paul Keim,Miguel Jose Yacaman +15 more
TL;DR: In this paper, a very distinct spectroscopic signature of the SARS-CoV-2 virus can be obtained using surface enhanced Raman spectroscopy (SERS) of virion particles.
Journal ArticleDOI
Burkholderia pseudomallei, the causative agent of melioidosis, is rare but ecologically established and widely dispersed in the environment in Puerto Rico.
Carina M. Hall,Sierra A. Jaramillo,Rebecca Jimenez,Nathan E. Stone,Heather Centner,Joseph D. Busch,Nicole Bratsch,Chandler C. Roe,Jay E. Gee,Alex R. Hoffmaster,Sarai Rivera-Garcia,Fred Soltero,Kyle Ryff,Janice Perez-Padilla,Paul Keim,Jason W. Sahl,David M. Wagner +16 more
TL;DR: Phylogeographic patterns suggest the source of B. pseudomallei populations in Puerto Rico and elsewhere in the Caribbean may have been Central or South America.
Journal ArticleDOI
Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro .
Nathan E. Stone,Sierra A. Jaramillo,Ashley N Jones,Adam J. Vazquez,Madison Martz,Lora M. Versluis,Marlee O. Raniere,Haley E Nunnally,Katherine E. Zarn,Roxanne Nottingham,Ken R. Ng,Jason W. Sahl,David M. Wagner,Steen Knudsen,Erik W. Settles,Paul Keim,Christopher T French +16 more
TL;DR: Evaluated a new poly(ADP-ribose) polymerase (PARP) inhibitor, stenoparib, that recently advanced to phase II clinical trials for treatment of ovarian cancer, for activity against human respiratory coronaviruses, including SARS-CoV-2, in vitro, showing strong antiviral activity.
Posted ContentDOI
The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus
Jianhua Yu,Wenjuan Dong,Aimin Li,Jianying Zhang,Michael A. Caligiuri,Sierra A. Jaramillo,Heather L. Mead,Nathan E. Stone,Ashley N Jones,Daniel R Kollath,Vanessa K Coyne,Martha Yearsley,Li-Shu Wang,Bridget M. Barker,Paul Keim,Tasha Barr +15 more
TL;DR: In this paper, the authors characterized the K18-hACE2 mouse model expressing human (h)ACE2 in mice, controlled by the human keratin 18 (K18) promoter in epithelia, including airway epithelial cells where SARS-CoV-2 infections typically start.