S
Silmara Marques Allegretti
Researcher at State University of Campinas
Publications - 76
Citations - 1505
Silmara Marques Allegretti is an academic researcher from State University of Campinas. The author has contributed to research in topics: Schistosoma mansoni & Schistosomiasis. The author has an hindex of 21, co-authored 73 publications receiving 1232 citations. Previous affiliations of Silmara Marques Allegretti include French Institute of Health and Medical Research.
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Journal ArticleDOI
Phytol, a Diterpene Alcohol from Chlorophyll, as a Drug against Neglected Tropical Disease Schistosomiasis Mansoni
Josué de Moraes,Rosimeire Nunes de Oliveira,Jéssica Pereira Costa,Antonio Luiz Gomes Júnior,Damião Pergentino de Sousa,Rivelilson Mendes de Freitas,Silmara Marques Allegretti,Pedro Luiz Silva Pinto +7 more
TL;DR: Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, possesses promising antischistosomal properties in vitro and in a mouse model of schistosomiasis mansoni, and validates phytol as a promising drug and offers the potential of a new direction for chemotherapy of human schistOSomiasis.
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Schistosoma mansoni: In vitro schistosomicidal activity of essential oil of Baccharis trimera (less) DC
Rosimeire Nunes de Oliveira,Vera Lúcia Garcia Rehder,Adriana da Silva Santos de Oliveira,Ílio Montanari Junior,João Carvalho,Ana Lúcia Tasca Gois Ruiz,Verónica de Lourdes Sierpe Jeraldo,Arício Xavier Linhares,Silmara Marques Allegretti +8 more
TL;DR: It was possible to notice a significant decline in the motility of the worms and a mortality rate of 100% 30 h after they had been exposed to the essential oil in the concentration of 130 μg/mL, the first time that the schistosomicidal activity has been reported for essential oil of B. trimera (less) DC.
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Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni.
Rosimeire Nunes de Oliveira,Vera Lúcia Garcia Rehder,Adriana da Silva Santos de Oliveira,Verónica de Lourdes Sierpe Jeraldo,Arício Xavier Linhares,Silmara Marques Allegretti +5 more
TL;DR: In conclusion, B. trimera exhibits major schistosomicidal effects in vivo against immature and adult worms of S. mansoni, opening up perspectives for future researches on substance or compound isolation and the elucidation of its mechanisms of action.
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Molecular detection of Hepatozoon spp. in Brazilian and exotic wild carnivores.
Marcos Rogério André,Cristina Harumi Adania,Rodrigo Hidalgo Friciello Teixeira,G.H. Vargas,M. Falcade,L. Sousa,A.R. Salles,Silmara Marques Allegretti,Paulo A.N. Felippe,Rosangela Zacarias Machado +9 more
TL;DR: The presence of Hepatozoon spp.
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In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment.
Ana Luiza R. de Souza,Tatiana Andreani,Rosimeire Nunes de Oliveira,Charlene P. Kiill,Fernanda Kolenyak dos Santos,Silmara Marques Allegretti,Marco Vinícius Chaud,Eliana B. Souto,Amélia M. Silva,Maria Palmira Daflon Gremião +9 more
TL;DR: PZQ-loaded SLN could be a new drug delivery system for the schistosomiasis treatment especially in marginalized communities, improving the therapeutic efficacy and reducing the toxic effects of PZQ.