scispace - formally typeset
S

Simon G. Thompson

Researcher at University of Cambridge

Publications -  251
Citations -  83209

Simon G. Thompson is an academic researcher from University of Cambridge. The author has contributed to research in topics: Randomized controlled trial & Abdominal aortic aneurysm. The author has an hindex of 88, co-authored 235 publications receiving 68436 citations.

Papers
More filters
Journal ArticleDOI

Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI

Mendelian randomization analysis with multiple genetic variants using summarized data.

TL;DR: It is concluded that Mendelian randomization investigations using summarized data from uncorrelated variants are similarly efficient to those using individual‐level data, although the necessary assumptions cannot be so fully assessed.
Journal ArticleDOI

Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

Emanuele Di Angelantonio, +64 more
- 20 Aug 2016 - 
TL;DR: The associations of both overweight and obesity with higher all-cause mortality were broadly consistent in four continents and supports strategies to combat the entire spectrum of excess adiposity in many populations.
Journal ArticleDOI

Interpreting findings from Mendelian randomization using the MR-Egger method

TL;DR: There are several reasons why causal estimates from the MR-Egger method may be biased and have inflated Type 1 error rates in practice, including violations of the InSIDE assumption and the influence of outlying variants.