Author
Simon W. Banting
Other affiliations: University of Melbourne, Peter MacCallum Cancer Centre, Box Hill Hospital
Bio: Simon W. Banting is an academic researcher from St. Vincent's Health System. The author has contributed to research in topics: Cholecystectomy & Endoscopic retrograde cholangiopancreatography. The author has an hindex of 15, co-authored 33 publications receiving 2861 citations. Previous affiliations of Simon W. Banting include University of Melbourne & Peter MacCallum Cancer Centre.
Papers
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Heidelberg University1, University of Edinburgh2, Flinders Medical Centre3, Royal Prince Alfred Hospital4, University of Tokyo5, Memorial Sloan Kettering Cancer Center6, University of Melbourne7, St. Vincent's Health System8, Alfred Hospital9, Nagoya University10, University of Adelaide11, Royal North Shore Hospital12, University of Texas MD Anderson Cancer Center13, Toronto General Hospital14, University of Hong Kong15, University of Girona16
TL;DR: A definition and grading of severity of posthepatectomy liver failure is proposed, which can be used in future studies to allow objective and accurate comparisons of operative interventions in the field of hepatic surgery.
1,597 citations
Heidelberg University1, University of Edinburgh2, Flinders Medical Centre3, University of Hong Kong4, Nagoya University5, Royal Prince Alfred Hospital6, University of Tokyo7, University of Melbourne8, St. Vincent's Health System9, Alfred Hospital10, University of Adelaide11, Royal North Shore Hospital12, University of Texas MD Anderson Cancer Center13, Toronto General Hospital14, University of Girona15, Memorial Sloan Kettering Cancer Center16
TL;DR: A uniform definition and severity grading of bile leakage is proposed to enable a standardized comparison of the results of different clinical trials and may facilitate an objective evaluation of diagnostic and therapeutic modalities in the field of hepatobiliary and pancreatic operative therapy.
1,240 citations
Heidelberg University1, University of Edinburgh2, Flinders Medical Centre3, University of Adelaide4, Royal North Shore Hospital5, University of Hong Kong6, Nagoya University7, University of Girona8, University of Texas MD Anderson Cancer Center9, Memorial Sloan Kettering Cancer Center10, Toronto General Hospital11, Alfred Hospital12, St. Vincent's Health System13, Royal Prince Alfred Hospital14, University of Melbourne15, University of Tokyo16
TL;DR: The proposed definition and grading of severity of PHH enables valid comparisons of results from different studies and should be applied in future trials to standardize reporting of complications.
Abstract: Background A standardized definition of post-hepatectomy haemorrhage (PHH) has not yet been established. Methods An international study group of hepatobiliary surgeons from high-volume centres was convened and a definition of PHH was developed together with a grading of severity considering the impact on patients' clinical management. Results The definition of PHH varies strongly within the hepatic surgery literature. PHH is defined as a drop in haemoglobin level >3 g/dl post-operatively compared with the post-operative baseline level and/or any post-operative transfusion of packed red blood cells (PRBC) for a falling haemoglobin and/or the need for radiological intervention (such as embolization) and/or re-laparotomy to stop bleeding. Evidence of intra-abdominal bleeding should be obtained by imaging or blood loss via the abdominal drains if present. Transfusion of up to two units of PRBC is considered as being Grade A PHH. Grade B PHH requires transfusion of more than two units of PRBC, whereas the need for invasive re-intervention such as embolization and/ or re-laparotomy defines Grade C PHH. Conclusion The proposed definition and grading of severity of PHH enables valid comparisons of results from different studies. It is easily applicable in clinical routine and should be applied in future trials to standardize reporting of complications. A proposed international definition and grading of severity of post hepatectomy haemorrhage which may enable better comparison of outcomes from future published studies
317 citations
TL;DR: In this article, Magnetic Resonance cholangiopancreatography (MRCP) was used to diagnose choledocholithiasis and biliary strictures in a large number of patients.
129 citations
TL;DR: Predominantly retrospective and uncontrolled studies suggest that surgery and locoregional techniques may prolong survival in Uveal melanoma patients with liver metastases.
Abstract: Background Uveal melanoma (UM) is a rare malignancy with a propensity for metastasis to the liver. Systemic chemotherapy is typically ineffective in these patients with liver metastases and overall survival is poor. There are no evidence-based guidelines for management of UM liver metastases. The aim of this study was to review the evidence for management of UM liver metastases. Methods A systematic review of English literature publications was conducted across Ovid Medline, Ovid MEDLINE and Cochrane CENTRAL databases until April 2019. The primary outcome was overall survival, with disease free survival as a secondary outcome. Results 55 studies were included in the study, with 2446 patients treated overall. The majority of these studies were retrospective, with 17 of 55 including comparative data. Treatment modalities included surgery, isolated hepatic perfusion (IHP), hepatic artery infusion (HAI), transarterial chemoembolization (TACE), selective internal radiotherapy (SIRT) and Immunoembolization (IE). Survival varied greatly between treatments and between studies using the same treatments. Both surgery and liver-directed treatments were shown to have benefit in selected patients. Conclusion Predominantly retrospective and uncontrolled studies suggest that surgery and locoregional techniques may prolong survival. Substantial variability in patient selection and study design makes comparison of data and formulation of recommendations challenging.
54 citations
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TL;DR: The following Clinical Practice Guidelines will give up-to-date advice for the clinical management of patients with hepatocellular carcinoma, as well as providing an in-depth review of all the relevant data leading to the conclusions herein.
7,851 citations
TL;DR: It is demonstrated that EUS-FNA is a highly accurate diagnostic test for solid neoplasms of the pancreas and should be considered when algorithms for investigating solid pancreatic lesions are being planned.
585 citations
TL;DR: Consider conservative or endoscopic/percutaneous measures if: Localised perforation with no extravasation No significant fluid collections No significant retroperitoneal emphysema Stable patient.
571 citations
TL;DR: Surgical treatment of perihilar cholangiocarcinoma has been evolving steadily, with expanded surgical indication, decreased mortality, and increased survival, with lymph node metastasis was the strongest prognostic indicator.
Abstract: Objective:To review our 34-year experience with 574 consecutive resections for perihilar cholangiocarcinoma and to evaluate the progress made in surgical treatment of this disease.Background:Few studies have reported improved surgical outcomes for perihilar cholangiocarcinoma; therefore, it is still
490 citations
TL;DR: The interpretation of the routinely performed liver tests along with the indications and utility of quantitative tests are discussed, including the Model for End Stage Liver Disease rather than any single parameter.
Abstract: Interpretation of abnormalities in liver function tests is a common problem faced by clinicians. This has become more common with the introduction of automated routine laboratory testing. Not all persons with one or more abnormalities in these tests actually have liver disease. The various biochemical tests, their pathophysiology, and an approach to the interpretation of abnormal liver function tests are discussed in this review.
425 citations