Sin-Doo Lee

Bio: Sin-Doo Lee is an academic researcher from Seoul National University. The author has contributed to research in topics: Liquid crystal & Liquid-crystal display. The author has an hindex of 24, co-authored 271 publications receiving 2251 citations. Previous affiliations of Sin-Doo Lee include Samsung.

Topographic control of lipid-raft reconstitution in model membranes

Abstract: Liquid-ordered (LO) domains reconstituted in model membranes1,2,3,4,5,6 have provided a useful platform for in vitro studies of the lipid-raft model7,8,9, in which signalling membrane molecules are thought to be compartmentalized in sphingolipid- and cholesterol-rich domains. These in vitro studies, however, have relied on an uncontrolled phase-separation process that gives a random distribution of LO domains. Obviously, a precise control of the size and spatial distribution of the LO domains would enable a more systematic large-scale in vitro study of the lipid-raft model. The prerequisite for such capability would be the generation of a well-defined energy landscape for reconstituting the LO domain without disrupting the two-dimensional (2D) fluidity of the model membrane. Here we report controlling the reconstitution of the LO domains in a spatially selective manner by predefining a landscape of energy barriers using topographic surface modifications. We show that the selective reconstitution spontaneously arises from the 2D brownian motion of nanoscale LO domains and signalling molecules captured in these nanodomains, which in turn produce a prescribed, concentrated downstream biochemical process. Our approach opens up the possibility of engineering model biological membranes by taking advantage of the intrinsic 2D fluidity. Moreover, our results indicate that the topographic configuration of cellular membranes could be an important machinery for controlling the lipid raft in vivo.

3D/2D convertible projection-type integral imaging using concave half mirror array.

Abstract: We propose a new method for implementing 3D/2D convertible feature in the projection-type integral imaging by using concave half mirror array. The concave half mirror array has the partially reflective characteristic to the incident light. And the reflected term is modulated by the concave mirror array structure, while the transmitted term is unaffected. With such unique characteristic, 3D/2D conversion or even the simultaneous display of 3D and 2D images is also possible. The prototype was fabricated by the aluminum coating and the polydimethylsiloxane molding process. We could experimentally verify the 3D/2D conversion and the display of 3D image on 2D background with the fabricated prototype.

Polarization-insensitive liquid crystal Fresnel lens of dynamic focusing in an orthogonal binary configuration

Abstract: We report on a polarization-insensitive liquid crystal (LC) Fresnel lens with the centrosymmetry of dynamic focusing in an orthogonally alternating hybrid configuration. The polarization-insensitive Fresnel lens having such successive orthogonal hybrid alignment in two adjacent zones was fabricated using a single-masking process through two-step exposure of a linearly polarized ultraviolet light. It was found that the dynamic focusing property of the LC Fresnel lens is electrically controllable and entirely centrosymmetrical irrespective of the polarization state of an incident light.

Alignment layerless flexible liquid crystal display fabricated by an imprinting technique at ambient temperature

Abstract: The authors report on an alignment layerless (AL) flexible liquid crystal (LC) display fabricated at ambient temperature through an imprinting process. One-dimensional microgrooves and two-dimensional arrays of microstructures embossed on plastic substrates provide the spontaneous alignment of the LC molecules and spacers for the uniform cell gap in a flexible LC display, respectively. It is found that the azimuthal anchoring energy, generated from the microgrooves, is on the order of 10−5J∕m2 which is strong enough to uniformly align the LC over large area. Our AL flexible LC display shows symmetric viewing characteristics and stable electro-optic properties under a bent environment.

Thiol–Ene Click Chemistry

Abstract: Following Sharpless' visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions. Herein, we review the radical-mediated thiol-ene reaction as one such click reaction. This reaction has all the desirable features of a click reaction, being highly efficient, simple to execute with no side products and proceeding rapidly to high yield. Further, the thiol-ene reaction is most frequently photoinitiated, particularly for photopolymerizations resulting in highly uniform polymer networks, promoting unique capabilities related to spatial and temporal control of the click reaction. The reaction mechanism and its implementation in various synthetic methodologies, biofunctionalization, surface and polymer modification, and polymerization are all reviewed.

Micromachining a miniaturized capillary electrophoresis-based chemical analysis system on a chip

Abstract: Micromachining technology was used to prepare chemical analysis systems on glass chips (1 centimeter by 2 centimeters or larger) that utilize electroosmotic pumping to drive fluid flow and electrophoretic separation to distinguish sample components. Capillaries 1 to 10 centimeters long etched in the glass (cross section, 10 micrometers by 30 micrometers) allow for capillary electrophoresis-based separations of amino acids with up to 75,000 theoretical plates in about 15 seconds, and separations of about 600 plates can be effected within 4 seconds. Sample treatment steps within a manifold of intersecting capillaries were demonstrated for a simple sample dilution process. Manipulation of the applied voltages controlled the directions of fluid flow within the manifold. The principles demonstrated in this study can be used to develop a miniaturized system for sample handling and separation with no moving parts.

Phase transitions in lyotropic colloidal and polymer liquid crystals

Abstract: An overview is given of theory and experiments on liquid crystal phases which appear in solutions of elongated colloidal particles or stiff polymers. The Onsager (1949) virial thecry for the isotropionematic transition of thin rodlike particles is treated comprehensively along with extensions to polydisperse solutions and soft interactions. Computer simulations of liquid crystal phases in hard particle fluids are summarized and used to assess the quality of statistical mechanical thwries for stiff panicles at higher dume haion-like the inclusion of higher Virial coefficients, yexpansion, scaled particle theory and density functional theory. Both computer simulations and density functional theory indicate formation of more highly ordered smectic phases. The range of experimental applicability h strongly widened by the extension of the viriai theory to wormlike chains by Khokhlov and Semenov (1981, 1982). Fmally, experimental results for a number of carefully studied, charged and uncharged colloids and polymers are summarized and wmpared to theoretical results. IE many cases the agreement is semi-quantitative.

Soft matter with hard skin : From skin wrinkles to templating and material characterization

Abstract: The English-language dictionary defines wrinkles as "small furrows, ridges, or creases on a normally smooth surface, caused by crumpling, folding, or shrinking". In this paper we review the scientific aspects of wrinkling and the related phenomenon of buckling. Specifically, we discuss how and why wrinkles/buckles form in various materials. We also describe several examples from everyday life, which demonstrate that wrinkling or buckling is indeed a commonplace phenomenon that spans a multitude of length scales. We will emphasize that wrinkling is not always a frustrating feature (e.g., wrinkles in human skin), as it can help to assemble new structures, understand important physical phenomena, and even assist in characterizing chief material properties.