S
Sindre Lee
Researcher at University of Oslo
Publications - 29
Citations - 1145
Sindre Lee is an academic researcher from University of Oslo. The author has contributed to research in topics: Adipose tissue & Skeletal muscle. The author has an hindex of 16, co-authored 29 publications receiving 820 citations. Previous affiliations of Sindre Lee include Oslo University Hospital.
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Journal ArticleDOI
Irisin – a myth rather than an exercise-inducible myokine
Elke Albrecht,Frode Norheim,Bernd Thiede,Torgeir Holen,Tomoo Ohashi,Lisa Schering,Sindre Lee,Julia Brenmoehl,Selina Thomas,Christian A. Drevon,Harold P. Erickson,Steffen Maak +11 more
TL;DR: The results call into question all previous data obtained with commercial ELISA kits for irisin, and provide evidence against a physiological role for irisin in humans and other species.
Journal ArticleDOI
The myokine decorin is regulated by contraction and involved in muscle hypertrophy.
Timo Kanzleiter,Michaela Rath,Sven W. Görgens,Jørgen Jensen,Daniel S. Tangen,Anders J. Kolnes,Kristoffer Jensen Kolnes,Kristoffer Jensen Kolnes,Sindre Lee,Jürgen Eckel,Annette Schürmann,Kristin Eckardt +11 more
TL;DR: The findings suggest that decorin secreted from myotubes in response to exercise is involved in the regulation of muscle hypertrophy and hence could play a role in exercise-related restructuring processes of skeletal muscle.
Journal ArticleDOI
The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle.
Timothy M. Moore,Zhenqi Zhou,Whitaker Cohn,Frode Norheim,Amanda J. Lin,Nareg Y. Kalajian,Alexander R. Strumwasser,Kevin Cory,Kate Whitney,Theodore Ho,Timothy Ho,Joseph L. Lee,Daniel H. Rucker,Orian S. Shirihai,Alexander M. van der Bliek,Julian P. Whitelegge,Marcus M. Seldin,Aldons J. Lusis,Sindre Lee,Christian A. Drevon,Sushil K. Mahata,Lorraine P. Turcotte,Andrea L. Hevener +22 more
TL;DR: The findings highlight the importance of mitochondrial dynamics, specifically Drp1 signaling, in the regulation of exercise performance and adaptations to endurance exercise training.
Journal ArticleDOI
Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines.
Shirin Pourteymour,Kristin Eckardt,Torgeir Holen,Torgrim Mikal Langleite,Sindre Lee,Jørgen Arendt Jensen,Kåre I. Birkeland,Christian A. Drevon,Marit Hjorth,Marit Hjorth +9 more
TL;DR: In this paper, the authors used mRNA sequencing as an untargeted approach to study gene expression of secreted proteins in skeletal muscle upon acute as well as long-term exercise and identified 17 new, exercise-responsive transcripts encoding secretory proteins.
Journal ArticleDOI
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling.
Zhenqi Zhou,Timothy M. Moore,Brian G. Drew,Vicent Ribas,Jonathan Wanagat,Mete Civelek,Mayuko Segawa,Dane M. Wolf,Frode Norheim,Marcus M. Seldin,Alexander R. Strumwasser,Kate Whitney,Ellen Lester,Britany R. Reddish,Laurent Vergnes,Karen Reue,Prashant Rajbhandari,Peter Tontonoz,Jason T. Lee,Sushil K. Mahata,Sushil K. Mahata,Sylvia C. Hewitt,Orian S. Shirihai,Craig Gastonbury,Kerrin S. Small,Markku Laakso,Jørgen Arendt Jensen,Sindre Lee,Christian A. Drevon,Kenneth S. Korach,Aldons J. Lusis,Andrea L. Hevener +31 more
TL;DR: It is shown that adipose tissue ESR1/Esr1 expression inversely associated with adiposity and positively associated with genes involved in mitochondrial metabolism and markers of metabolic health in 700 Finnish men and 100 strains of inbred mice from the UCLA Hybrid Mouse Diversity Panel.