S
Siu Kai Kong
Researcher at The Chinese University of Hong Kong
Publications - 166
Citations - 5118
Siu Kai Kong is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Surface plasmon resonance & Biosensor. The author has an hindex of 38, co-authored 164 publications receiving 4414 citations.
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Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach–Zehnder configuration
TL;DR: A high-sensitivity surface plasmon resonance (SPR) biosensor based on the Mach-Zehnder interferometer design is presented and a significant improvement over previously obtained results should allow SPR biosensors to become a possible replacement for conventional biosensing techniques based on fluorescence.
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Tendon‐derived stem cells (TDSCs) promote tendon repair in a rat patellar tendon window defect model
Ming Ni,Pauline Po Yee Lui,Yunfeng Rui,Yuk Wa Lee,Yuk Wai Lee,Qi Tan,Yin Mei Wong,Siu Kai Kong,Pui Man Lau,Gang Li,Kai Ming Chan +10 more
TL;DR: TDSCs promoted earlier and better repair in a rat patellar tendon window defect model, as indicated by the increase in collagen production and improvement of cell alignment, collagen fiber alignment and collagen birefringence typical of tendon.
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Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft.
Mei-Sze Lee,Judy Chan Yuet-Wa,Siu Kai Kong,Biao Yu,Vincent Ooi Eng-Choon,Henry Wong Nai-Ching,Thomas Mak Chung-Wai,Kwok-Pui Fung +7 more
TL;DR: In vivo study demonstrated that daily administration of polyphyllin D through intravenous injection for ten days in nude mice bearing MCF-7 cells effectively reduced tumor growth for 50% in terms of tumor weight and size, given no significant toxicity in heart and liver to the host.
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The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells
Patrick Tik Wan Law,Chi Hang Wong,Thomas Chi Chuen Au,Chi Pang Chuck,Siu Kai Kong,Paul K.S. Chan,Ka Fai To,Anthony W.I. Lo,Judy Yuet-Wa Chan,Yick Keung Suen,Edwin Kin Wai Chan,Kwok-Pui Fung,Mary M.Y. Waye,Joseph J.Y. Sung,Y.M. Dennis Lo,Stephen Kwok-Wing Tsui +15 more
TL;DR: It is shown that overexpression of a single SARS-CoV protein can induce apoptosis in vitro, and in vitro experiments of chromatin condensation and DNA fragmentation suggested that the 3a protein may trigger apoptosis.
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Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells
Jenny Y.N. Cheung,Rose C.Y. Ong,Y. K. Suen,Vincent E.C. Ooi,Henry N. C. Wong,Thomas C. W. Mak,Kwok-Pui Fung,Biao Yu,Siu Kai Kong +8 more
TL;DR: It is shown for the first time that PD is a potent anticancer agent that can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.