S
Siyuan Chen
Researcher at Sichuan University
Publications - 8
Citations - 315
Siyuan Chen is an academic researcher from Sichuan University. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 4, co-authored 8 publications receiving 125 citations.
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Epigenetic regulation of macrophages: from homeostasis maintenance to host defense.
TL;DR: This review focuses on key epigenetic events associated with macrophage fate, highlighting events related to the maintenance of tissue homeostasis, responses to different stimuli and the formation of innate immune memory.
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Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin
TL;DR: Wang et al. as discussed by the authors used immunohistochemical analysis of CXCR2 on the microarray of tumor tissues of clinical lung adenocarcinoma and lung squamous cell carcinoma patients.
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Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer
Heng Zheng,Yan Tie,Zhen Fang,Xiao-Ai Wu,Tao Yi,Shuang Huang,Xiao Liang,Yanping Qian,Xi Wang,Ruyu Pi,Siyuan Chen,Yong Peng,Shengyong Yang,Xia Zhao,Xiawei Wei +14 more
TL;DR: It is found that the high expression of JMJD6 in ovarian cancer was correlated with poor prognosis in ovariancancer and that SKLB325 may be a potential candidate drug for the treatment of ovarian cancer.
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Jumonji domain-containing protein 6 protein and its role in cancer.
TL;DR: The structure and functions ofJMJD6 are summarized, with particular emphasis on the role of JMJD6 in cancer progression.
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Silver nanoparticles and silver ions cause inflammatory response through induction of cell necrosis and the release of mitochondria in vivo and in vitro.
Lu Li,Zhenfei Bi,Yuzhu Hu,Lu Sun,Yanlin Song,Siyuan Chen,Fei Mo,Jingyun Yang,Yuquan Wei,Xiawei Wei +9 more
TL;DR: It is validated that small amounts of silver ions dissolved from silver nanoparticles caused the depolarization of plasma membrane, resulting in an overload of intracellular sodium and calcium, and eventually led to the cell necrosis.