Siyuan Ma

TL;DR: MaAsLin 2 (Microbiome Multivariable Associations with Linear Models) as mentioned in this paper uses generalized linear and mixed models to accommodate a wide variety of modern epidemiological studies, including cross-sectional and longitudinal designs, as well as a variety of data types with or without covariates and repeated measurements.

TL;DR: A baseline investigation of variability in taxonomic profiling for the Microbiome Quality Control project baseline study finds variations depended most on biospecimen type and origin, followed by DNA extraction, sample handling environment, and bioinformatics.

TL;DR: These findings provide a mechanistic link between EVs and vascular dysfunction during malaria infection and show that EVs are efficiently internalized by endothelial cells, where the miRNA-Argonaute 2 complexes modulate target gene expression and barrier properties.

TL;DR: It is suggested that the bone marrow is an important reservoir for gametocyte development and proliferation of malaria parasites, and a systematic examination of tissue sequestration during P. vivax infection has important implications for parasite diagnosis and treatment.

TL;DR: Current best practices for experimental design in microbiome molecular epidemiology are surveyed, including technologies for generating, analyzing, and integrating microbiome multiomics data.